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The World Economic Forum's (WEF) flagship annual report surveyed 750 experts to identify the most significant global concerns. Here are the top five:

Each year, Future 500 releases a report of what we predict will be the most critical social and environmental issues driving corporate-stakeholder engagement in the coming year. This year, we anticipate that corporations will be challenged to go even further than last year, using their economic influence on policy and politicians while being asked to take a bigger stand on global issues.

In 2016, we predict that stakeholders will continue to organize around issues like chemicals, water scarcity and local control of resources, challenging the private sector to drive change in their supply chains, make more time bound commitments and be more transparent. We anticipate increased focus on women impacting the global economy and concern around global ocean health, an issue moving to the forefront of our list.