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Anastrozole comes as a tablet to take by mouth. It is usually taken once a day with or without food. Take anastrozole at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take anastrozole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
In an accompanying editorial, Kathleen I. Pritchard of the Toronto Sunnybrook Regional Cancer Center in Ontario, Canada, wrote: "Now, for women nearing completion of five years of tamoxifen, the decision to consider additional years of endocrine therapy with an aromatase inhibitor seems fairly straightforward." Patients should talk to their doctors about which aromatase inhibitor (Anastrozole; letrozole; exemestane) might make sense for them, given the different short- and long-term side effects and the patient'S own medical history.
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Nastrozol appears slowly, T1 / 2 - 40-50 hours Anastrozole and its metabolites are excreted primarily in urine (Less than 10% of the derived dose - unchanged) within 72 h after dosing.
Arimidex, with the generic name of Anastrozole, works by blocking the usage of estrogen by certain cases of cancer requiring estrogen to maturate.
Take in this medication by mouth with or without snack, regularly one time a day, or as indicated by your doctor. Take in these pills usually in order to reach the mainly goods from it. Mention to take in it at the similar hour day by day. Use the remedy right as indicated by your doctor. Its banned use the preparation in more times or for more than recommended. Follow the indications on your prescription is typically taken one time on a day. The patient may need to keep taking in Anastrozole for up to 5 years. Follow your doctorsinstructions.
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Although the current recommendation is that 5 years of anastrozole be given, it is possible that a longer or shorter treatment program will be recommended in the future.
That were 19 and 9 times higher than the respective values found in postmenopausal volunteers at the recommended dose resulted in hypertrophy of the ovaries and the presence of follicular cysts. In addition, hyperplastic uteri were observed in 6-month studies in female dogs administered doses equal to or greater than 1 mg/kg/day which produced plasma anastrozole C.
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