Canonical processing of APP is catalyzed by α-secretase, resulting in the generation of two fragments: a large extracellular fragment secreted APP (sAPP) α (sAPPα) that is released to extracellular medium, as well as an83 amino acid C-terminal fragment α-carboxyterminal fragments (CTF) that remains in the membrane.
Low levels of vitamin D may raise a person's risk of premature death, a study by Johns Hopkins researchers shows.
The research followed other recent studies showing low levels of vitamin D are linked to certain cancers, diabetes, and bone and immune system problems, but this is the first research to connect vitamin D deficiency to a higher risk of death
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