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Drug and Iron Chelation Therapy Drugs to treat hemochromatosis: iron accumulation in the blood is one of the most immediate consequences resulting from frequent blood transfusions, which needs a thalassemia. To cope with hemochromatosis, the doctor suggests, generally, a therapy with chelating drugs, which can, therefore, to sequester the iron accumulated in the blood and eliminate it through urination.

The side effects of chelation therapy may include head ache, nausea, and vomiting, gastric upsets, fever, convulsions, heart arrhythmia, respiratory failure, low blood pressure and bone marrow damage.