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Matti Narkia

Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human... - 0 views

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    Docosahexaenoic acid suppresses arachidonic acid-induced proliferation of LS-174T human colon carcinoma cells.
    Habbel P, Weylandt KH, Lichopoj K, Nowak J, Purschke M, Wang JD, He CW, Baumgart DC, Kang JX.
    World J Gastroenterol. 2009 Mar 7;15(9):1079-84.
    PMID: 19266600
    doi: 10.3748/wjg.15.1079.
Matti Narkia

DHA reduces tumor growth - Life Extension Update - 0 views

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    Mice injected with cancer cells experienced significantly elevated levels of C-reactive protein, white blood cells, and lipid peroxidation compared with control mice. These levels were reduced in animals that received cisplatin and/or DHA. While treatment with 125 mg/kg DHA inhibited tumor growth by 38 percent compared to untreated animals, 250 mg/kg suppressed tumor growth by 79 percent, which was a greater effect than that of cisplatin alone (which was associated with a 55 percent reduction). The combination of DHA and cisplatin resulted in an 81 percent inhibition of growth, while reducing elevated white blood cell levels (leukocytosis) to normal levels. Treatment with the higher dose of DHA alone was associated with a similar reduction in white blood cells, which, when elevated, are associated with tumor growth. A strong relationship was observed between tumor growth and white blood cell levels as well as C-reactive protein levels.

    In another experiment with rats treated with cisplatin, the addition of 250 mg/kg DHA prevented lethal kidney toxicity in 88 percent of the animals that received it, while none of the rats that received cisplatin alone survived.
Matti Narkia

Omega-3 Kills Cancer Cells - 0 views

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    ScienceDaily (Apr. 5, 2009) - Docosahexanoic acid (DHA), an omega-3 fatty acid found in fish oils, has been shown to reduce the size of tumours and enhance the positive effects of the chemotherapy drug cisplatin, while limiting its harmful side effects. The rat experiments provide some support for the plethora of health benefits often ascribed to omega-3 acids.
Matti Narkia

The Heart Scan Blog: What your doctor doesn't know about heart disease - 0 views

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    What causes coronary heart disease or coronary atherosclerotic plaque, this thing that we track with heart scans? \n\nWell, here are a few little-publicized facts about heart disease that you are unlikely to hear from your When's-the-next-stent? cardiologist or the What is there besides statins? primary care doctor. \n\n(Since everybody knows that smoking is a modifiable risk for heart disease that can be readily identified, let's focus on the blood tests that reveal heart disease causes.)
Matti Narkia

Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in... - 0 views

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    Dietary linolenic acid is inversely associated with calcified atherosclerotic plaque in the coronary arteries: the National Heart, Lung, and Blood Institute Family Heart Study.
    Djoussé L, Arnett DK, Carr JJ, Eckfeldt JH, Hopkins PN, Province MA, Ellison RC; Investigators of the NHLBI FHS.
    Circulation. 2005 Jun 7;111(22):2921-6. Epub 2005 May 31.
    PMID: 15927976
    doi: 10.1161/CIRCULATIONAHA.104.489534
Matti Narkia

A meta-analytic review of double-blind, placebo-controlled trials of antidepressant eff... - 0 views

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    Lin PY, Su KP.
    A meta-analytic review of double-blind, placebo-controlled trials of antidepressant efficacy of omega-3 fatty acids.
    J Clin Psychiatry. 2007 Jul;68(7):1056-61.
    PMID: 17685742 [PubMed - in process]
Matti Narkia

Effects of omega-3 polyunsaturated fatty acids on depression - [Herz. 2006] - PubMed Re... - 0 views

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    Severus WE.
    Effects of omega-3 polyunsaturated fatty acids on depression.
    Herz. 2006 Dec;31 Suppl 3:69-74. Review.
    PMID: 17575808 [PubMed - indexed for MEDLINE]
Matti Narkia

Depressive Symptoms, omega-6:omega-3 Fatty Acids, and Inflammation in Older Adults -- K... - 0 views

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    Kiecolt-Glaser JK, Belury MA, Porter K, Beversdorf DQ, Lemeshow S, Glaser R.
    Depressive symptoms, omega-6:omega-3 fatty acids, and inflammation in older adults.
    Psychosom Med. 2007 Apr;69(3):217-24. Epub 2007 Mar 30.
    PMID: 17401057 [PubMed - indexed f
Matti Narkia

Omega-3 fatty acids and cardiac arrhythmias: prior studies and recommendations for futu... - 0 views

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    Omega-3 fatty acids and cardiac arrhythmias: prior studies and recommendations for future research: a report from the National Heart, Lung, and Blood Institute and Office Of Dietary Supplements Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop.\nLondon B, Albert C, Anderson ME, Giles WR, Van Wagoner DR, Balk E, Billman GE, Chung M, Lands W, Leaf A, McAnulty J, Martens JR, Costello RB, Lathrop DA.\nCirculation. 2007 Sep 4;116(10):e320-35. Review. \nPMID: 17768297
Matti Narkia

AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, Nationa... - 0 views

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    AHA Science Advisory: Lyon Diet Heart Study. Benefits of a Mediterranean-style, National Cholesterol Education Program/American Heart Association Step I Dietary Pattern on Cardiovascular Disease.\nKris-Etherton P, Eckel RH, Howard BV, St Jeor S, Bazzarre TL; Nutrition Committee Population Science Committee and Clinical Science Committee of the American Heart Association.\nCirculation. 2001 Apr 3;103(13):1823-5. \nPMID: 11282918
Matti Narkia

n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefi... - 0 views

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    Wang C, Harris WS, Chung M, Lichtenstein AH, Balk EM, Kupelnick B, Jordan HS, Lau J. \nn-3 Fatty acids from fish or fish-oil supplements, but not \nalpha-linolenic acid, benefit cardiovascular disease outcomes in \nprimary- and secondary-prevention studies: a systematic review. \nAm J Clin Nutr. 2006 Jul;84(1):5-17. Review. \nPMID: 16825676
Matti Narkia

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocar... - 0 views

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    Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico.\nLancet. 1999 Aug 7;354(9177):447-55. Erratum in: Lancet 2001 Feb 24;357(9256):642. Lancet. 2007 Jan 13;369(9556):106.\nPMID: 10465168
Matti Narkia

n-3 fatty acid dietary recommendations and food sources to achieve essentiality and car... - 0 views

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    n-3 fatty acid dietary recommendations and food sources to achieve essentiality and cardiovascular benefits.\nGebauer SK, Psota TL, Harris WS, Kris-Etherton PM.\nAm J Clin Nutr. 2006 Jun;83(6 Suppl):1526S-1535S. Review.\nPMID: 16841863
Matti Narkia

Omega-3 Fatty Acids Prevent Medical Complications Of Obesity, Study Suggests - 0 views

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    ScienceDaily (Feb. 12, 2009) - According to a recent study, diets rich in omega-3 fatty acids protect the liver from damage caused by obesity and the insulin resistance it provokes. This research should give doctors and nutritionists valuable information when recommending and formulating weight-loss diets and help explain why some obese patients are more likely to suffer some complications associated with obesity. Omega-3 fatty acids can be found in canola oil and fish.
Matti Narkia

Novel Benefits Of Fatty Acids In Arteries Shown - 0 views

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    ScienceDaily (Feb. 11, 2009) - New research from Columbia University Medical Center continues to shed light on the benefits of making fish a staple of any diet.
Matti Narkia

Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary h... - 0 views

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    Prevention of sudden cardiac death with omega-3 fatty acids in patients with coronary heart disease: A meta-analysis of randomized controlled trials.\nZhao YT, Chen Q, Sun YX, Li XB, Zhang P, Xu Y, Guo JH.\nAnn Med. 2009 Jan 16:1-10. [Epub ahead of print]\nPMID: 19148838
Matti Narkia

Mortality and cancer incidence in cohorts of Swedish fishermen and fishermen's wives: u... - 0 views

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    Mortality and cancer incidence in cohorts of Swedish fishermen and fishermen's wives: updated findings.\nMikoczy Z, Rylander L.\nChemosphere. 2009 Feb;74(7):938-43. Epub 2008 Nov 28.\nPMID: 19041115
Matti Narkia

Mortality in a cohort with high fish consumption. - 0 views

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    Mortality in a cohort with high fish consumption.\nTurunen AW, Verkasalo PK, Kiviranta H, Pukkala E, Jula A, Männistö S, Räsänen R, Marniemi J, Vartiainen T.\nInt J Epidemiol. 2008 Oct;37(5):1008-17. Epub 2008 Jun 25.\nPMID: 18579573
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