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I'm defining a base font-size of 62.5% to have the convenience of sizing rems in a way that is similar to using px.

The compounding nature of em-based font-sizing can be frustrating so what else can we do?

Scott Kellum said on 2 March 2012 at 4:06 pm: After much deliberation over here: https://github.com/h5bp/html5-boilerplate/issues/1005#issuecomment-4293007 Jonathan Neal suggested a method using font: 0/0 serif; and things seem to be settling on this — .ir { font: 0/0 serif; text-shadow: none; color: transparent; }

While I think this is certainly and interesting approach, I have some concerns with the accessibility. In some, if not all, cases when overflow: hidden; hides the content of the element this is applied to from screen readers. In most cases where I use image replacement, I still need the text to be accessible (e.g. call to action buttons set in Gotham). See Aaron Gustafson’s A List Apart article, http://www.alistapart.com/articles/now-you-see-me/. Has anyone tested this with a wide battery of screen readers or other accessibility devices?

Another note on accessibility: Besides the screen reader problems – people who don’t get images will not see the text too.

As a few people said already, this does not solve the accessibility problem that comes with text-indent. Worse, it may send the wrong message: “this is new and cool, use this from now!”. As a leader in the industry, I think you should warn people that even if this is “better” in term of performance, it is still a bad solution. Imo, Image Replacement techniques should be evaluated against the problems they solve/address. Fwiw, I wrote something about these challenges a few years back: http://tjkdesign.com/articles/tip.asp </shameless plug>