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Matti Narkia

Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. - [Lancet. 1989] - PubMed Result - 0 views

www.ncbi.nlm.nih.gov/...2572900

1989 November Lancet study research epidemiological humans vitamin_D serum 25ohd colon cancer colon_cancer Garland Cedric Frank nutrition medline

shared by Matti Narkia on 24 Sep 09 - No Cached
  • Matti Narkia on 24 Sep 09
     
    Serum 25-hydroxyvitamin D and colon cancer: eight-year prospective study. Garland CF, Comstock GW, Garland FC, Helsing KJ, Shaw EK, Gorham ED. Lancet. 1989 Nov 18;2(8673):1176-8. PMID: 2572900 Blood samples taken in 1974 in Washington County, Maryland, from 25 620 volunteers were used to investigate the relation of serum 25-hydroxyvitamin D (25-OHD) with subsequent risk of getting colon cancer. 34 cases of colon cancer diagnosed between August, 1975, and January, 1983, were matched to 67 controls by age, race, sex, and month blood was taken. Risk of colon cancer was reduced by 75% in the third quintile (27-32 ng/ml) and by 80% in the fourth quintile (33-41 ng/ml) of serum 25-OHD. Risk of getting colon cancer decreased three-fold in people with a serum 25-OHD concentration of 20 ng/ml or more. The results are consistent with a protective effect of serum 25-OHD on colon cancer.
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