This web site is dedicated to vitamin D and cancer. This is because exciting new research indicates that vitamin D-whether produced in the skin as a result of exposure to ultraviolet radiation (from sunlight or sun lamps) or obtained from supplementation with cholecalciferol (vitamin D3)-may help cancer patients. However, the research is far from complete.
Vitamin d and its role in cancer and immunity: a prescription for sunlight.
Mullin GE, Dobs A.
Nutr Clin Pract. 2007 Jun;22(3):305-22. Review.
PMID: 17507731
(free full text PDF available)
A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer.
Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL.
J Natl Cancer Inst. 2007 Jul 18;99(14):1120-9. Epub 2007 Jul 10.
PMID: 17623801
Addressing the health benefits and risks, involving vitamin D or skin cancer, of increased sun exposure.\nMoan J, Porojnicu AC, Dahlback A, Setlow RB.\nProc Natl Acad Sci U S A. 2008 Jan 15;105(2):668-73. Epub 2008 Jan 7.\nPMID: 18180454
Holick MF.
Vitamin D: its role in cancer prevention and treatment.
Prog Biophys Mol Biol. 2006 Sep;92(1):49-59. Epub 2006 Mar 10. Review.
PMID: 16566961 [PubMed - indexed for MEDLINE]
Giovannucci E, Liu Y, Rimm EB, Hollis BW, Fuchs CS, Stampfer MJ, Willett WC.
Prospective study of predictors of vitamin D status and cancer incidence and mortality in men.
J Natl Cancer Inst. 2006 Apr 5;98(7):451-9.
PMID: 16595781 [PubMed - indexed fo
Grant WB, Holick MF.
Benefits and requirements of vitamin D for optimal health: a review.
Altern Med Rev. 2005 Jun;10(2):94-111. Review.
PMID: 15989379 [PubMed - indexed for MEDLINE]
Zittermann A.
Vitamin D in preventive medicine: are we ignoring the evidence?
Br J Nutr. 2003 May;89(5):552-72. Review.
PMID: 12720576 [PubMed - indexed for MEDLINE]
Grant WB, Garland CF, Gorham ED.
An estimate of cancer mortality rate reductions in Europe and the US with 1,000 IU of oral vitamin D per day.
Recent Results Cancer Res. 2007;174:225-34.
PMID: 17302200 [PubMed - in process]
Knight JA, Lesosky M, Barnett H, Raboud JM, Vieth R.
Vitamin D and reduced risk of breast cancer: a population-based case-control study.
Cancer Epidemiol Biomarkers Prev. 2007 Mar;16(3):422-9.
PMID: 17372236 [PubMed - indexed for MEDLINE]
ScienceDaily (Sep. 1, 2005) - STANFORD, Calif. - The growth of prostate cancer cells can be halted by combining a form of vitamin D, available only by prescription, with low doses of an over-the-counter painkiller, researchers at the Stanford University School of Medicine have found. The combination reduced prostate cancer cell growth in a laboratory dish by up to 70 percent, according to the findings, published in the Sept. 1 issue of Cancer Research.
Li H, Stampfer MJ, Hollis JBW, Mucci LA, Gaziano JM, et al. (2007)
A Prospective Study of Plasma Vitamin D Metabolites, Vitamin D Receptor Polymorphisms, and Prostate Cancer.
PLoS Med 4(3): e103
doi:10.1371/journal.pmed.0040103
Mullin GE, Dobs A.
Vitamin d and its role in cancer and immunity: a prescription for sunlight.
Nutr Clin Pract. 2007 Jun;22(3):305-22. Review.
PMID: 17507731 [PubMed - indexed for MEDLINE]
Robien K, Cutler GJ, Lazovich D.
Vitamin D intake and breast cancer risk in postmenopausal women: the Iowa Women's Health Study.
Cancer Causes Control. 2007 Sep;18(7):775-82. Epub 2007 Jun 5.
PMID: 17549593 [PubMed - in process]