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Matti Narkia

Interleukin 2-mediated conversion of ovarian cancer-associated CD4+ regulatory T cells ... - 0 views

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    Interleukin 2-mediated conversion of ovarian cancer-associated CD4+ regulatory T cells into proinflammatory interleukin 17-producing helper T cells.
    Leveque L, Deknuydt F, Bioley G, Old LJ, Matsuzaki J, Odunsi K, Ayyoub M, Valmori D.
    J Immunother. 2009 Feb-Mar;32(2):101-8.
    PMID: 19238008
    doi: 10.1097/CJI.0b013e318195b59e

    Thus, although the impact of TH17 cells on the evolution of EOC remains to be established, our data suggest that local IL-2 treatment in ovarian cancer may result in the conversion of tumor-associated Treg into TH17 cells, relieve Treg-mediated suppression, and contribute to enhance antitumor immunity.
Matti Narkia

Inhibition of suppressor T lymphocytes (Ts) by cimetidine. - J Immunol. 1987 May - 0 views

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    Inhibition of suppressor T lymphocytes (Ts) by cimetidine.
    Sahasrabudhe DM, McCune CS, O'Donnell RW, Henshaw EC.
    J Immunol. 1987 May 1;138(9):2760-3.
    PMID: 2952721

    Cyclophosphamide (CY) is the most extensively studied inhibitor of suppressor T lymphocyte (Ts) function. However, repeated administration of CY can abrogate sensitization. Therefore, we were interested in identifying noncytotoxic inhibitors of Ts function as adjuncts in the immunotherapy of Ts-inducing murine tumors. The effect of cimetidine (a histamine type 2 receptor antagonist) and diphenhydramine (a histamine type 1 receptor antagonist) on the Ts mediating tolerance to 2,4-dinitrofluorobenzene was studied. We report our data regarding the specific inhibition of Ts by cimetidine.
Matti Narkia

Effects of perioperative cimetidine administration on peripheral blood lymphocytes and ... - 0 views

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    Effects of perioperative cimetidine administration on peripheral blood lymphocytes and tumor infiltrating lymphocytes in patients with gastrointestinal cancer: results of a randomized controlled clinical trial.
    Li Y, Yang GL, Yuan HY, Bai DJ, Wang K, Lin CR, Hu MB, Feng MH.
    Hepatogastroenterology. 2005 Mar-Apr;52(62):504-8.
    PMID: 15816467
Matti Narkia

Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and... - 0 views

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    Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial.
    Gogos CA, Ginopoulos P, Salsa B, Apostolidou E, Zoumbos NC, Kalfarentzos F.
    Cancer. 1998 Jan 15;82(2):395-402.
    PMID: 9445198
Matti Narkia

Nutrient Intake and Immune Function of Elderly Subjects - J Am Diet Assoc. 2008 Dec - 0 views

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    Nutrient intake and immune function of elderly subjects.
    Wardwell L, Chapman-Novakofski K, Herrel S, Woods J.
    J Am Diet Assoc. 2008 Dec;108(12):2005-12.
    PMID: 19027403
    doi:10.1016/j.jada.2008.09.003
Matti Narkia

Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cel... - 0 views

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    Platelets and fibrin(ogen) increase metastatic potential by impeding natural killer cell-mediated elimination of tumor cells.
    Palumbo JS, Talmage KE, Massari JV, La Jeunesse CM, Flick MJ, Kombrinck KW, Jirousková M, Degen JL.
    Blood. 2005 Jan 1;105(1):178-85. Epub 2004 Sep 14.
    PMID: 15367435
    DOI 10.1182/blood-2004-06-2272
Matti Narkia

Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell. - [Med... - 0 views

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    Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell.
    Wang JS, Chung Y, Chow SE.
    Med Sci Sports Exerc. 2009 Jan;41(1):115-22.
    PMID: 19092699
Matti Narkia

Beta Glucan Research - 0 views

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    Beta glucan is a scientifically proven biological defense modifier (BDM) that nutritionally potentiates and modulates the immune response. As a supplement, after swallowing orally, Beta glucan is ingested primarily through macrophage and dendritic immune cells, to nutritionally and safely yield, through immune response potentiation and modulation, in many instances various therapeutic healing effects generated by the immune cells.  For many years Glucans have been investigated (History) for these immune enhancing properties, particularly their ability to activate macrophage immune cells and NK-Cells, plus in turn, the T-Cells, and B-Cells including selected cytokines and complement. 
Matti Narkia

Evaluation of active hexose correlated compound hepatic metabolism and potential for dr... - 0 views

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    Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents.
    Mach CM, Fugii H, Wakame K, Smith J.
    J Soc Integr Oncol. 2008 Summer;6(3):105-9.
    PMID: 19087767
Matti Narkia

[Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of ... - 0 views

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    [Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]
    Duan P, Wang ZM.
    Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Jul;22(7):515-7. Chinese.
    PMID: 12592686
Matti Narkia

Structure-function relationships of anthocyanins from various anthocyanin-rich extracts... - 0 views

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    Structure-function relationships of anthocyanins from various anthocyanin-rich extracts on the inhibition of colon cancer cell growth.
    Jing P, Bomser JA, Schwartz SJ, He J, Magnuson BA, Giusti MM.
    J Agric Food Chem. 2008 Oct 22;56(20):9391-8. Epub 2008 Sep 19.
    PMID: 18800807
    DOI: 10.1021/jf8005917
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