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Matti Narkia

Vitamin D and Its Role in Cancer and Immunity: A Prescription for Sunlight -- Mullin an... - 0 views

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    Vitamin d and its role in cancer and immunity: a prescription for sunlight.
    Mullin GE, Dobs A.
    Nutr Clin Pract. 2007 Jun;22(3):305-22. Review.
    PMID: 17507731
    DOI: 10.1177/0115426507022003305
Matti Narkia

Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disea... - 0 views

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    Th1/Th2 balance: the hypothesis, its limitations, and implications for health and disease.
    Kidd P.
    Altern Med Rev. 2003 Aug;8(3):223-46. Review.
    PMID: 12946237

    Th1 pathways typically produce activation
    of cytotoxic T lymphocytes (Tc), NK cells,
    macrophages, and monocytes, all of which can
    attack cancer cells and generally defend against
    tumors.55 IFN-gamma and other Th1 cytokines are
    typically lower in advanced cancer patients, while
    the Th2 marker IL-4 can be higher or unchanged
Matti Narkia

Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and... - 0 views

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    Dietary omega-3 polyunsaturated fatty acids plus vitamin E restore immunodeficiency and prolong survival for severely ill patients with generalized malignancy: a randomized control trial.
    Gogos CA, Ginopoulos P, Salsa B, Apostolidou E, Zoumbos NC, Kalfarentzos F.
    Cancer. 1998 Jan 15;82(2):395-402.
    PMID: 9445198
Matti Narkia

Nutrient Intake and Immune Function of Elderly Subjects - J Am Diet Assoc. 2008 Dec - 0 views

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    Nutrient intake and immune function of elderly subjects.
    Wardwell L, Chapman-Novakofski K, Herrel S, Woods J.
    J Am Diet Assoc. 2008 Dec;108(12):2005-12.
    PMID: 19027403
    doi:10.1016/j.jada.2008.09.003
Matti Narkia

The effect of dietary omega-3 polyunsaturated fatty acids on T-lymphocyte subsets of pa... - 0 views

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    The effect of dietary omega-3 polyunsaturated fatty acids on T-lymphocyte subsets of patients with solid tumors.
    Gogos CA, Ginopoulos P, Zoumbos NC, Apostolidou E, Kalfarentzos F.
    Cancer Detect Prev. 1995;19(5):415-7.
    PMID: 7585727
Matti Narkia

IMMUNE SYSTEM STRENGTHENING - lefeurope.com - 0 views

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    Age, stress, and poor nutrition can sap our immune system of its effectiveness. Influenza provides one example. During young adulthood, when the body can mount a robust immune response to this common virus, influenza is rarely fatal. Among the elderly, however, the virus is associated with significant rates of death and hospitalization (Nichol KL 2005).

    The impact of aging on the immune system is profound. As people age, a number of critical immune system components are reduced or slowed, including cellular response, response to vaccines, and antibody production. At the same time, susceptibilities to infection and cancer are increased. Some of this increased susceptibility to disease is linked to chronic inflammation, which is associated with many disorders of aging (Ershler WB et al 2000; Hamerman D 1999; Taaffe DR et al 2000).
Matti Narkia

Definition of beta-glucan - National Cancer Institute Drug Dictionary - 0 views

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    beta-glucan
    A polysaccharide isolated from the cell walls of bacteria, plants, and fungi with immunostimulant and antineoplastic activities. In a solubilized form, beta-glucan binds to a lectin site within complement receptor 3 (CR3) on leukocytes, priming the receptor to trigger cytotoxic degranulation of leukocytes when leukocyte CR3 binds to complement 3 (iC3b)-coated tumors. Thus, the attachment of beta-glucan to CR3 of circulating leukocytes simulates leukocytes to kill iC3b-coated tumor cells in the same way as they kill iC3b-coated yeast. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Matti Narkia

Beta-glucan - Wikipedia, the free encyclopedia - 0 views

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    β-Glucans (or beta-glucans) are polysaccharides of D-glucose monomers linked by glycosidic bonds. They occur most commonly as cellulose in plants and trees, the bran of cereal grains, the cell wall of baker's yeast, certain types of fungi, and many kinds of mushrooms and bacteria. Some forms of beta glucans are useful in human nutrition as texturing agents and as soluble fiber supplements, but problematic in brewing as excessive levels make the wort too viscous. Yeast derived beta glucans are notable for their immunomodulatory function
Matti Narkia

The application of probiotics in cancer - Br J Nutr. 2007 Oct (full text) - 0 views

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    The application of probiotics in cancer.
    de Moreno de LeBlanc A, Matar C, Perdigón G.
    Br J Nutr. 2007 Oct;98 Suppl 1:S105-10. Review.
    PMID: 17922945
    doi:10.1017/S0007114507839602
Matti Narkia

Sloan-Kettering - Garlic - 0 views

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    Derived from the bulb or clove of the plant. Garlic is used as a spice and to treat hyperlipidemia, hypertension, atherosclerosis, cancer, and infections. Processing can have a substantial effect on the chemical content in garlic; the volatile oil components are sensitive to heat and certain enzymes are acid-labile. Several oral garlic formulations are available, and clinical studies have addressed a variety of the proposed claims. Placebo-controlled trials on the cholesterol lowering effect of garlic yielded mixed results (16) (17) (18) (21) (22) (26). Studies evaluating the antithrombotic effects repeatedly have shown modest reduction in platelet aggregation, but varying levels of fibrinolytic activity. Research shows mixed effects with regard to reductions in blood glucose, blood pressure, or risk of cardiovascular disease (23). Frequently reported adverse events include bad breath, headache, fatigue, GI upset, diarrhea, sweating, and possible hypoglycemia (9). Because garlic is known to decrease platelet aggregation and potentially elevate the INR, it should not be used with anticoagulants or in patients with platelet dysfunction (15). Garlic appears to induce cytochrome p450 3A4 and may enhance metabolism of many medications (e.g. cyclosporin and saquinavir) (12). An analysis of several case-control studies in Europe suggests an inverse association between garlic consumption and risk of common cancers (25).
Matti Narkia

Evaluation of active hexose correlated compound hepatic metabolism and potential for dr... - 0 views

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    Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents.
    Mach CM, Fugii H, Wakame K, Smith J.
    J Soc Integr Oncol. 2008 Summer;6(3):105-9.
    PMID: 19087767
Matti Narkia

Sloan-Kettering - AHCC - 0 views

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    A proprietary extract prepared from co-cultured mycelia of several species of Basidiomycete mushrooms, including shiitake (Lentinus edodes), active hexose correlated compound (AHCC) is extracted from mushrooms using hot water following an enzyme pretreatment, but specific mushroom source and preparation details have not been fully disclosed. Patients use this to prevent and treat cancer. Animal studies suggest that AHCC has antioxidant effects and may protect against disorders induced by oxidative stress (1) and may also enhance resistance against bacterial (2) (7)and viral infections (3). In healthy humans, AHCC increased dendritic cell number and function (4)

    In vitro and animal studies show that AHCC exhibits some anticancer activities, but the results of these studies are vague
Matti Narkia

Active Hexose Correlated Compound - Wikipedia, the free encyclopedia - 0 views

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    Active Hexose Correlated Compound (AHCC) is an alpha-glucan rich nutritional supplement produced from the mycelia of shiitake (Lentinula edodes) of the basidiomycete family of mushrooms, and should not be confused or used as a drug or medicine.[1][2] AHCC was originally designed to lower high-blood pressure. However, researchers at Tokyo University found AHCC's influence upon the innate immune system highly beneficial and published the results in 1992, though not in the commonly indexed scientific literature. In this study, researchers found that AHCC significantly increased natural killer (NK) cell activity in cancer patients, and also enhanced the effects of killer T-cells, and cytokines (interferon, IL-12, TNF-alpha
Matti Narkia

White button mushrooms appear to boost immune function - Tufts Journal: Briefs: Healthy... - 0 views

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    White button mushrooms appear to boost immune function

    It appears that a little fungus may be good for what ails you. That's the conclusion of a new study that found that eating white button mushrooms may boost the immune system and protect against infection.

    If the research, done on animals, translates to people, it could raise the health-benefit profile of the fungus, which also contains high concentrations of the super-antioxidant ergothioneine, which protects cells from damaging free radicals.

    "This is the first published study showing the effect of white button mushrooms on immune function," Dayong Wu, a scientist in the Immunology Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts and lead author of the study, published in the June issue of the Journal of Nutrition, told NutraIngredients.com.

    The research also suggests that the mushroom may boost both innate and acquired immune system health. The innate immune system, the one you're born with, is the body's first line of defense. The acquired immune system revs up if a pathogen makes its way past the innate system and customizes the immune response to target the invader.
Matti Narkia

Eating mushrooms may boost immune system (ASU Research) - 0 views

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    Edible mushrooms are a versatile functional food and have been touted as a way to preserve youth, longevity and overall health for centuries. Now nutrition researchers from Arizona State University and Pennsylvania State University are finding that they may even help boost the immune system and reduce inflammation, especially in the colon.

    Keith R. Martin, ASU assistant professor in nutrition, along with his Penn State colleagues, experimented with various types of mushrooms, from the more common white button to the exotic like shiitake and oyster, to see what sort of effect they had on the immune system. Their paper was published in late February in BMC Immunology, a peer reviewed online journal.

    "We found that the white button mushroom seemed to be the most effective in boosting the immune system, which is good because they are the most affordable," said Martin.
Matti Narkia

Coriolus versicolor and cancer (June 2003) - 0 views

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    Attached please find the final draft of Dr. Kenyon's non-controlled observational study on the use of Coriolus versicolor (non-extracted) in 30 solid tumour cancer patients. The final report will be published in the February edition of Mycology News 7.
    The patients were Stage III and Stage IV patients in which chemotherapy and radiotherapy were not considered successful. Below please find a synopsis of patient type.
Matti Narkia

Selenium and the immune response: 2. Enhancement of murine cytotoxic T-lymphocyte and n... - 0 views

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    2:
    Selenium and the immune response: 2. Enhancement of murine cytotoxic T-lymphocyte and natural killer cell cytotoxicity in vivo.
    Petrie HT, Klassen LW, Klassen PS, O'Dell JR, Kay HD.
    J Leukoc Biol. 1989 Mar;45(3):215-20.
    PMID: 2564412
Matti Narkia

Selenium and immunocompetence in patients with head and neck cancer. - Biol Trace Elem ... - 0 views

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    Selenium and immunocompetence in patients with head and neck cancer.
    Kiremidjian-Schumacher L, Roy M, Glickman R, Schneider K, Rothstein S, Cooper J, Hochster H, Kim M, Newman R.
    Biol Trace Elem Res. 2000 Feb;73(2):97-111.
    PMID: 11049203
    DOI: 10.1385/BTER:73:2:97
Matti Narkia

Arginine and immunity. - J Nutr. 2007 Jun - 0 views

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    Arginine and immunity.
    Popovic PJ, Zeh HJ 3rd, Ochoa JB.
    J Nutr. 2007 Jun;137(6 Suppl 2):1681S-1686S. Review.
    PMID: 17513447
Matti Narkia

Arginine and cancer. - J Nutr. 2004 Oct - 0 views

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    Arginine and cancer.
    Lind DS.
    J Nutr. 2004 Oct;134(10 Suppl):2837S-2841S; discussion 2853S. Review.
    PMID: 15465796
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