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Matti Narkia

A systematic review of the anticancer properties of berberine, a natural product from C... - 0 views

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    A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.
    Sun Y, Xun K, Wang Y, Chen X.
    Anticancer Drugs. 2009 Oct;20(9):757-69.
    PMID: 19704371
Matti Narkia

Berberine Inhibits Metastasis of Nasopharyngeal Carcinoma 5-8F Cells by Targeting Rho K... - 0 views

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    Berberine inhibits metastasis of nasopharyngeal carcinoma 5-8F cells by targeting Rho kinase-mediated Ezrin phosphorylation at threonine 567.
    Tang F, Wang D, Duan C, Huang D, Wu Y, Chen Y, Wang W, Xie C, Meng J, Wang L, Wu B, Liu S, Tian D, Zhu F, He Z, Deng F, Cao Y.
    J Biol Chem. 2009 Oct 2;284(40):27456-66. Epub 2009 Aug 3.
    PMID: 19651779
Matti Narkia

Berberine and Coptidis Rhizoma as novel antineoplastic agents: A review of traditional ... - 0 views

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    Berberine and Coptidis rhizoma as novel antineoplastic agents: a review of traditional use and biomedical investigations.
    Tang J, Feng Y, Tsao S, Wang N, Curtain R, Wang Y.
    J Ethnopharmacol. 2009 Oct 29;126(1):5-17. Epub 2009 Aug 15.
    PMID: 19686830
    doi:10.1016/j.jep.2009.08.009

    Conclusions
    The modern evidences of treating cancer with Huanglian and berberine have a strong linkage with traditional concept and rules of using Huanglian in CM practice. As anticancer candidates with low toxicity, berberine and its altered structure, as well as Huanglian and its formulae, will attract scientists to pursue the potential anticancer effects and the mechanisms by using technologies of genomics, proteomics and other advanced approaches. On the other hand, relatively few in vivo studies have been conducted on anticancer effects of Huanglian and berberine. The clinical application of berberine or Huanglian as novel cancer therapeutic agents requires in vivo validations and further investigations of their anticancer mechanisms.
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