Integrative Cancer Science and Therapeutics (ICST) is an open access, peer-reviewed online journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science. The Journal is concerned with basic, translational and clinical research, across different disciplines and areas, enhancing insight in understanding, prevention, diagnosis and treatment of cancer. The journal also prioritizes clinical trials evaluating new treatments, accompanied by research on pharmacology and molecular alterations or biomarkers that predict response or resistance to treatment.
International Journal of Cancer Studies & Research (IJCR) ISSN:2167-9118 is a comprehensive, peer reviewed journal devoted to cancer studies and research. IJCR, published by SciDoc is an open access journal that includes high quality papers, which covers all major areas of Cancer and its related fields.
Patients with larynx cancer who received a three-drug combination of docetaxel, cisplatin and 5-fluorouracil (TPF) during induction chemotherapy were more likely to retain larynx function than were patients treated with cisplatin and 5-fluoruracil (PF) alone, according to data from a randomized controlled trial in the March 24 online issue of the Journal of the National Cancer Institute.
Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials.
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C
Int J Cancer. 2008 Sep 15;123(6):1227-39. Review.
PMID: 18623084
Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma.
Jalili A, Pinc A, Pieczkowski F, Karlhofer FM, Stingl G, Wagner SN.
J Dtsch Dermatol Ges. 2008 Dec;6(12):1066-9. English, German.
PMID: 19138272
DOI: 10.1111/j.1610-0387.2008.06861.x
Li H, Stampfer MJ, Hollis JBW, Mucci LA, Gaziano JM, et al. (2007)
A Prospective Study of Plasma Vitamin D Metabolites, Vitamin D Receptor Polymorphisms, and Prostate Cancer.
PLoS Med 4(3): e103
doi:10.1371/journal.pmed.0040103
Benefits of Vitamin D Supplementation
Joel M. Kauffman, Ph.D.
Journal of American Physicians and Surgeons
Volume 14 Number 2 - Summer 2009
Clinical trials show that vitamin D supplementation at higher
levels than previously recommended is beneficial for many
conditions. It decreases the frequency of falls and fractures, helps
prevent cardiovascular disease, and reduces symptoms of colds or
influenza. Benefits are also seen in diabetes mellitus, multiple
sclerosis, Crohn disease, pain, depression, and possibly autism.
Sunlight does not cause an overdose of vitamin D production,
and toxicity from supplementation is rare. Dose recommendations
are increasing, but appear to be lagging the favorable trial results. A
number of common drugs deplete vitamin D levels, and others may
limit its biosynthesis from sunlight.
People with adequate levels from sun exposure will not benefit
from supplementation. While dietary intake is helpful,
supplementation is better able to raise serum 25-hydroxyvitamin D ,
the major circulating metabolite, to the level now thought adequate,
30-50 ng/mL.
Where there is inadequate daily sun exposure, oral doses of
1,000-2,000 IU/d are now considered routine, with much higher
doses (up to 50,000 IU) for rapid repletion now considered safe.
The influence of processing and preservation on the retention of health-promoting compounds in broccoli.
Galgano F, Favati F, Caruso M, Pietrafesa A, Natella S.
J Food Sci. 2007 Mar;72(2):S130-5.
PMID: 17995854
DOI: 10.1111/j.1750-3841.2006.00258.x
You-Lin Qiao, Sanford M. Dawsey, Farin Kamangar, Jin-Hu Fan, Christian C. Abnet, Xiu-Di Sun, Laura Lee Johnson, Mitchell H. Gail, Zhi-Wei Dong, Binbing Yu, Steven D. Mark, and Philip R. Taylor. Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial.
Journal of the National Cancer Institute, 2009 March 24;
DOI: 10.1093/jnci/djp037
White button mushrooms appear to boost immune function
It appears that a little fungus may be good for what ails you. That's the conclusion of a new study that found that eating white button mushrooms may boost the immune system and protect against infection.
If the research, done on animals, translates to people, it could raise the health-benefit profile of the fungus, which also contains high concentrations of the super-antioxidant ergothioneine, which protects cells from damaging free radicals.
"This is the first published study showing the effect of white button mushrooms on immune function," Dayong Wu, a scientist in the Immunology Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts and lead author of the study, published in the June issue of the Journal of Nutrition, told NutraIngredients.com.
The research also suggests that the mushroom may boost both innate and acquired immune system health. The innate immune system, the one you're born with, is the body's first line of defense. The acquired immune system revs up if a pathogen makes its way past the innate system and customizes the immune response to target the invader.