Group items tagged

Vitamin D and prevention of breast cancer: pooled analysis.
Garland CF, Gorham ED, Mohr SB, Grant WB, Giovannucci EL, Lipkin M, Newmark H, Holick MF, Garland FC.
J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):708-11.
PMID: 17368188

CONCLUSIONS: Intake of 2000 IU/day of Vitamin D(3), and, when possible, very moderate exposure to sunlight, could raise serum 25(OH)D to 52 ng/ml, a level associated with reduction by 50% in incidence of breast cancer, according to observational studies.

Prospective study of predictors of vitamin D status and cancer incidence and mortality in men.
Giovannucci E, Liu Y, Rimm EB, Hollis BW, Fuchs CS, Stampfer MJ, Willett WC.
J Natl Cancer Inst. 2006 Apr 5;98(7):451-9.
PMID: 16595781
doi:10.1093/jnci/djj101

Conclusions: Low levels of vitamin D may be associated with increased cancer incidence and mortality in men, particularly for digestive-system cancers. The vitamin D supplementation necessary to achieve a 25(OH)D increment of 25 nmol/L may be at least 1500 IU/day.

Prospective study of predictors of vitamin D status and survival in patients with colorectal cancer
K Ng, B M Wolpin, J A Meyerhardt, K Wu, A T Chan, B W Hollis, E L Giovannucci, M J Stampfer, W C Willett and C S Fuchs
Br J Cancer 101: 916-923; advance online publication, August 18, 2009; doi:10.1038/sj.bjc.6605262

Vitamin D is associated with improved survival in early-stage non-small cell lung cancer patients.
Zhou W, Suk R, Liu G, Park S, Neuberg DS, Wain JC, Lynch TJ, Giovannucci E, Christiani DC.
Cancer Epidemiol Biomarkers Prev. 2005 Oct;14(10):2303-9.
PMID: 16214909

In conclusion, the joint effects of surgery season and recent vitamin D intake seem to be associated with the survival of early-stage non-small cell lung cancer patients.

Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer.
Ng K, Meyerhardt JA, Wu K, Feskanich D, Hollis BW, Giovannucci EL, Fuchs CS.
J Clin Oncol. 2008 Jun 20;26(18):2984-91.
PMID: 18565885
DOI: 10.1200/JCO.2007.15.1027

Conclusion Among patients with colorectal cancer, higher prediagnosis plasma 25(OH)D levels were associated with a significant improvement in overall survival. Further study of the vitamin D pathway and its influence on colorectal carcinogenesis and cancer progression is warranted.

A nested case control study of plasma 25-hydroxyvitamin D concentrations and risk of colorectal cancer.
Wu K, Feskanich D, Fuchs CS, Willett WC, Hollis BW, Giovannucci EL.
J Natl Cancer Inst. 2007 Jul 18;99(14):1120-9. Epub 2007 Jul 10.
PMID: 17623801