Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents.
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Best Pract Res Clin Endocrinol Metab. 2009 Feb;23(1):117-31.
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Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.
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J Clin Invest. 2003 Jan;111(1):43-50.
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Cannabinoids inhibit the vascular endothelial growth factor pathway in gliomas.
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Cancer Res. 2004 Aug 15;64(16):5617-23.
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Cannabinoids and cancer: causation, remediation, and palliation.
Hall W, Christie M, Currow D.
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Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
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"Compounds similar to those found in cannabis have been shown to stop prostate cancer cells from multiplying. Two cannabinoid compounds, JWH-015 and MET, stopped prostate tumour growth in human prostate cells in Petri dishes and also in mice with the disease. They halted the cell-division cycle and killed the cancer cells, and had the greatest effect on aggressive prostate cancer cell types, which do not respond to hormone treatments.
Some 192,000 men in the US alone are diagnosed with prostate cancer each year, and researchers Inés Díaz-Laviada Marturet at the University of Alcalá, Spain, and her colleagues say the results could offer hope to those affected. But before you go looking for a dealer, New Scientist answers a few questions"
By Randy Dotinga
HealthDay Reporter
MONDAY, Jan. 11 (HealthDay News) -- Preliminary research suggests that a combination of compounds in marijuana could help fight off a particularly deadly form of brain cancer.
But the findings shouldn't send patients rushing to buy pot: the levels used in the research appear to be too high to obtain through smoking. And there's no sign yet that the approach works in laboratory animals, let alone people.