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Matti Narkia

Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumul... - 0 views

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    Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma.
    Yoshiji H, Noguchi R, Toyohara M, Ikenaka Y, Kitade M, Kaji K, Yamazaki M, Yamao J, Mitoro A, Sawai M, Yoshida M, Fujimoto M, Tsujimoto T, Kawaratani H, Uemura M, Fukui H.
    J Hepatol. 2009 Aug;51(2):315-21. Epub 2009 May 15.
    PMID: 19501932

    CONCLUSIONS: The combination treatment of VK and ACE-I may suppress the cumulative recurrence of HCC after the curative therapy, at least partly through suppression of the VEGF-mediated neovascularization.
Matti Narkia

A systematic review of the anticancer properties of berberine, a natural product from C... - 0 views

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    A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.
    Sun Y, Xun K, Wang Y, Chen X.
    Anticancer Drugs. 2009 Oct;20(9):757-69.
    PMID: 19704371
Matti Narkia

Experimental Drug May Work In Many Cancers - 2 views

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    "SCIENTISTS have shown that a new class of cancer drugs called PARP inhibitors, currently being tested in clinical trials to treat breast and ovarian cancer could have dramatic results when used to treat other solid tumours, according to work presented at the NCRI Cancer Conference today. "
Matti Narkia

Scientists hail the first effective treatment for skin cancer victims - Hea... - 0 views

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    Scientists have developed the first "personalised" drug shown to be effective against advanced melanoma, the deadliest type of skin cancer which is on the rise in Britain.

    Warnings about the risks of melanoma were heightened this weekend as the fine weather drew thousands to sunbathe outdoors, putting them at increased risk. "Binge tanning", where sunbathers allow their skin to burn in their eagerness to get a tan, is a key cause of the cancer.

    Melanoma, which starts as a blemish or change to a mole on the skin, is treatable in its early stages but once it has spread to other organs such as the lungs and liver there are no treatment options. Patients with melanoma that has spread usually die within months
Matti Narkia

Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tu... - 0 views

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    Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer.
    Lönnroth C, Andersson M, Arvidsson A, Nordgren S, Brevinge H, Lagerstedt K, Lundholm K.
    Cancer Immun. 2008 Feb 29;8:5.
    PMID: 18307280

    MHC II protein (HLA-DP, -DQ, -DR) levels and infiltration by CD4+ T-helper cells of tumor stroma increased upon NSAID treatment, while CD8+ cytotoxic T-lymphocytes increased in both tumor stroma and epithelium. Molecules associated with immunosuppressive T regulatory cells (FOXP3, IL-10) were significantly decreased in indomethacin-exposed tumors. Standard oral administration of NSAID three days preoperatively was enough to increase tumor infiltration by seemingly activated immune cells. These findings agree with previous information that high pr
Matti Narkia

Experimental insulin-like growth factor receptor inhibitor reduced pancreatic cancer gr... - 0 views

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    PHILADELPHIA - Researchers at Amgen are testing a fully human monoclonal antibody that inhibits the activity of insulin-like growth factors (IGF-1 and IGF-2) and appears to reduce pancreatic cancer cells in early testing, according to a report in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research.
Matti Narkia

Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and prefe... - 0 views

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    Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer.
    Cerchietti LC, Navigante AH, Castro MA.
    Nutr Cancer. 2007;59(1):14-20.
    PMID: 17927497
Matti Narkia

CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependen... - 0 views

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    CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer.
    Ang JE, Olmos D, de Bono JS.
    Br J Cancer. 2009 Mar 10;100(5):671-5. Epub 2009 Feb 17.
    PMID: 19223900
    doi:10.1038/sj.bjc.6604904
Matti Narkia

Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms... - 0 views

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    Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.
    Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS.
    J Clin Oncol. 2008 Oct 1;26(28):4563-71. Epub 2008 Jul 21.
    PMID: 18645193
    DOI: 10.1200/JCO.2007.15.9749
Matti Narkia

Compound found in beans, nuts and cereals beats cancer (inositol pentakisphosphate) - 0 views

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    A collaborative study led by UCL (University College London) shows that the compound - inositol pentakisphosphate - found in beans, nuts and cereals inhibits a key enzyme (phosphoinositide 3-kinase) involved in tumour growth. The findings, published in the latest issue of Cancer Research, suggest that a diet enriched in such foods could help prevent cancer, while the inhibitor offers a new tool for anti-cancer therapy.
Matti Narkia

Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cuta... - 0 views

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    Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma.
    Jalili A, Pinc A, Pieczkowski F, Karlhofer FM, Stingl G, Wagner SN.
    J Dtsch Dermatol Ges. 2008 Dec;6(12):1066-9. English, German.
    PMID: 19138272
    DOI: 10.1111/j.1610-0387.2008.06861.x
Matti Narkia

Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxyg... - 0 views

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    Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck.
    Chen Z, Zhang X, Li M, Wang Z, Wieand HS, Grandis JR, Shin DM.
    Clin Cancer Res. 2004 Sep 1;10(17):5930-9.
    PMID: 15355926
Matti Narkia

In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human p... - 0 views

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    Jourdain C, Tenca G, Deguercy A, Troplin P, Poelman D. In-vitro effects of polyphenols from cocoa and beta-sitosterol on the growth of human prostate cancer and normal cells.
    Eur J Cancer Prev. 2006 Aug;15(4):353-61.
    PMID: 16835506 [PubMed - indexed fo
Matti Narkia

Zyflamend((R))-Mediated Inhibition of Human Prostate Cancer PC3 Cell Proliferation: Eff... - 0 views

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    Yang P, Cartwright C, Chan D, Vijjeswarapu M, Ding J, Newman RA.
    Zyflamend((R))-Mediated Inhibition of Human Prostate Cancer PC3 Cell Proliferation: Effects on 12-LOX and Rb Protein Phosphorylation.
    Cancer Biol Ther. 2007 Feb 25;6(2) [Epub ahead of pr
Matti Narkia

Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induc... - 0 views

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    Bemis DL, Capodice JL, Anastasiadis AG, Katz AE, Buttyan R.
    Zyflamend, a unique herbal preparation with nonselective COX inhibitory activity, induces apoptosis of prostate cancer cells that lack COX-2 expression.
    Nutr Cancer. 2005;52(2):202-12.
    PMID:
Matti Narkia

Ammonium tetrathiomolybdate - Wikipedia, the free encyclopedia - 0 views

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    Ammonium tetrathiomolybdate - Wikipedia, the free encyclopedia
Matti Narkia

Tetrathiomolybdate copper reduction anti-angiogenesis cancer treatment - anticopper, TM. - 0 views

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    WARNING: This page was NOT created or approved by any doctor or medical researcher. The purpose of this page is to provide hard-to-find information on copper reduction cancer treatment, a new unapproved and experimental course of cancer treatment whose ef
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