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Tonny Johnson

Cell Based Reporter Assays vs. Animal Studies in Drug Discovery- Potential Limitations,... - 0 views

This blog critically analyzes the potential scientific limitations, risks and liabilities of cell based reporter assays, including non-natural protein based reporter assays (e.g. circularly permute...

cell absed reporter assays drug discovery circularly permuted firefly luciferase

started by Tonny Johnson on 18 Jan 12 no follow-up yet
creativebiolabs

What You Need to Know About scFv/Fab - 0 views

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    Fragment antibody-binding (Fab fragment) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain of each of the heavy and the light chain. Single-chain variable fragment (scFv) is not actually a fragment of an antibody, but instead is a fusion protein of the variable regions of the heavy (VH) and light chains (VL) of immunoglobulins, connected with a short linker peptide of ten to about 25 amino acids.
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