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Matti Narkia

Sloan-Kettering - Coriolus Versicolor - 1 views

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    Coriolus versicolor is a mushroom of the Basidiomycetes class. It was used initially in Traditional Chinese medicine as a tonic, but recent studies suggest that it has immunostimulant and anti-tumor properties. Polysaccharide-K (PSK), a proprietary product derived from Coriolus, was developed for cancer treatment in Japan. When used as an adjuvant, PSK appears to improve survival rates in patients with gastric (1) (2) and colorectal (3) (4) (5) cancers. Other Coriolus extracts, such as polysaccharide-peptide (PSP) and VPS, are available as dietary supplements. When used in conjunction with chemotherapy, PSP may benefit patients with advanced non-small cell lung cancer (7). Other clinical studies using Coriolus extract alone or in combination with other botanicals also suggest positive immunomodulatory effects (8) (9). However, studies on breast cancer (10), hepatocellular carcinoma (11), and leukemia (12) produced mixed results. A hot water extract of Coriolus, VPS, was found to enhance development of large intestinal tumors in mice (21). Coriolus extracts are generally well tolerated but minor adverse effects have been reported.

    Many over-the-counter Coriolus products are not standardized, making it difficult to compare potency between brands. It is also unclear if PSK, PSP and other Coriolus extracts have comparable effects.
Matti Narkia

Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell... - 0 views

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    Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer.
    Tsang KW, Lam CL, Yan C, Mak JC, Ooi GC, Ho JC, Lam B, Man R, Sham JS, Lam WK.
    Respir Med. 2003 Jun;97(6):618-24.
    PMID: 12814145
    doi:10.1053/rmed.2003.1490
Matti Narkia

Coriolus versicolor extracts: relevance in cancer management (free full text PDF availa... - 0 views

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    Coriolus versicolor extracts: relevance in cancer management
    M. Szeto, BSC RD
    Curr Oncol. 2008 April; 15(2): 79.
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