Authors of the study reported that carnitine deficiency is a risk factor and should be viewed as a mechanism in hepatic carcinogenesis, and that long-term L-carnitine supplementation prevents the development of liver cancer. Therefore, carnitine supplementation alone or in combination with other natural chemopreventive compounds could be used to prevent, slow or reverse the occurrence of liver cance
Progression of diethylnitrosamine-induced hepatic carcinogenesis in carnitine-depleted rats.
Al-Rejaie SS, Aleisa AM, Al-Yahya AA, Bakheet SA, Alsheikh A, Fatani AG, Al-Shabanah OA, Sayed-Ahmed MM.
World J Gastroenterol. 2009 Mar 21;15(11):1373-80.
PMID: 19294768
Impact of antioxidant supplementation on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials.
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C
Int J Cancer. 2008 Sep 15;123(6):1227-39. Review.
PMID: 18623084