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Matti Narkia

Marijuana Compounds Could Beat Back Brain Cancer - Cancer Information (Cancers, Symptom... - 2 views

    By Randy Dotinga
    HealthDay Reporter

    MONDAY, Jan. 11 (HealthDay News) -- Preliminary research suggests that a combination of compounds in marijuana could help fight off a particularly deadly form of brain cancer.

    But the findings shouldn't send patients rushing to buy pot: the levels used in the research appear to be too high to obtain through smoking. And there's no sign yet that the approach works in laboratory animals, let alone people.
Matti Narkia

Briefing: Cannabis compounds fight prostate cancer - health - 19 August 2009 - New Scie... - 2 views

    "Compounds similar to those found in cannabis have been shown to stop prostate cancer cells from multiplying. Two cannabinoid compounds, JWH-015 and MET, stopped prostate tumour growth in human prostate cells in Petri dishes and also in mice with the disease. They halted the cell-division cycle and killed the cancer cells, and had the greatest effect on aggressive prostate cancer cell types, which do not respond to hormone treatments.

    Some 192,000 men in the US alone are diagnosed with prostate cancer each year, and researchers Inés Díaz-Laviada Marturet at the University of Alcalá, Spain, and her colleagues say the results could offer hope to those affected. But before you go looking for a dealer, New Scientist answers a few questions"
Matti Narkia

Marijuana Damages DNA And May Cause Cancer, New Test Reveals - 0 views

    ScienceDaily (June 15, 2009) - Using a highly sensitive new test, scientists in Europe are reporting "convincing evidence" that marijuana smoke damages the genetic material DNA in ways that could increase the risk of cancer.
Matti Narkia

Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid r... - 0 views

    Inhibition of skin tumor growth and angiogenesis in vivo by activation of cannabinoid receptors.
    Casanova ML, Blázquez C, Martínez-Palacio J, Villanueva C, Fernández-Aceñero MJ, Huffman JW, Jorcano JL, Guzmán M.
    J Clin Invest. 2003 Jan;111(1):43-50.
    PMID: 12511587
Matti Narkia

Cannabinoids and cancer: causation, remediation, and palliation : The Lancet Oncology - 0 views

    Cannabinoids and cancer: causation, remediation, and palliation.
    Hall W, Christie M, Currow D.
    Lancet Oncol. 2005 Jan;6(1):35-42. Review.
    PMID: 15629274
Matti Narkia

Cannabinoids: potential anticancer agents : Abstract : Nature Reviews Cancer - 0 views

    Cannabinoids: potential anticancer agents.
    Guzmán M.
    Nat Rev Cancer. 2003 Oct;3(10):745-55. Review.
    PMID: 14570037
Matti Narkia

Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2... - 0 views

    Cannabinoids inhibit glioma cell invasion by down-regulating matrix metalloproteinase-2 expression.
    Blázquez C, Salazar M, Carracedo A, Lorente M, Egia A, González-Feria L, Haro A, Velasco G, Guzmán M.
    Cancer Res. 2008 Mar 15;68(6):1945-52.
    PMID: 18339876
    doi: 10.1158/0008-5472.CAN-07-5176
Matti Narkia

Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agent... - 0 views

    Use of cannabinoid receptor agonists in cancer therapy as palliative and curative agents.
    Pisanti S, Malfitano AM, Grimaldi C, Santoro A, Gazzerro P, Laezza C, Bifulco M.
    Best Pract Res Clin Endocrinol Metab. 2009 Feb;23(1):117-31.
    PMID: 19285265
Matti Narkia

Cannabis compound slows lung cancer in mice - health - 18 April 2007 - New Scientist - 0 views

    The active compound in marijuana, THC, can slow the growth of lung tumours and reduce the spread of the cancer in mice, a preliminary study reveals.

    Human lung cancer tumours grew less than half as fast in mice that received moderate doses of the compound, the researchers reveal. They hope that drugs mimicking the apparent anti-cancer effects of tetrahydrocanabinol (THC) could one day help treat patients. The team strongly discourage people from self-medicating by smoking marijuana, noting that doing so could potentially encourage tumour growth.
Matti Narkia

Cannabis destroys cancer cells... reveals research at Barts and The London, Queen Mary'... - 0 views

    Researchers investigating the role of cannabis in cancer therapy reveal it has the potential to destroy leukaemia cells, in a paper published in the March 2006 edition of Letters in Drug Design & Discovery.  Led by Dr Wai Man Liu, at Barts and the London, Queen Mary's School of Medicine and Dentistry, the team has followed up on their findings of 2005 which showed that the main active ingredient in cannabis, tetrahydrocannabinol, or THC, has the potential to be used effectively against some forms of cancer.  Dr Liu has since moved to the Institute of Cancer in Sutton where he continues his work into investigating the potential therapeutic benefit of new anti-cancer agents.
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