Astragalus root is used in traditional medicine for its immunestimulating properties. Chinese studies suggest that astragalus, when used with angelica, has renal protective effects (6). In addition, astragalus decreases the proteinuria associated with idiopathic membranous nephropathy (7) as well as possesses natriuretic action (8). Astragalus may also suppress airway hyperreactivity associated with allergic asthma in vivo (9). An herbal formula using astragalus as a major ingredient has been shown to reduce fatigue in athletes (10). Furthermore, astragalus increases M-cholinergic receptor density in senile rats (11), which suggests that it may have a role in combating senility.
In vitro and in vivo immunomodulating and immunorestorative effects of Astragalus membranaceus.
Cho WC, Leung KN.
J Ethnopharmacol. 2007 Aug 15;113(1):132-41. Epub 2007 May 31.
PMID: 17611061
doi:10.1016/j.jep.2007.05.020
[Clinical study on effect of Astragalus in efficacy enhancing and toxicity reducing of chemotherapy in patients of malignant tumor]
Duan P, Wang ZM.
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002 Jul;22(7):515-7. Chinese.
PMID: 12592686
Traditional Chinese medicine Astragalus reverses predominance of Th2 cytokines and their up-stream transcript factors in lung cancer patients.
Wei H, Sun R, Xiao W, Feng J, Zhen C, Xu X, Tian Z.
Oncol Rep. 2003 Sep-Oct;10(5):1507-12.
PMID: 12883732
In vitro and in vivo anti-tumor effects of Astragalus membranaceus.
Cho WC, Leung KN.
Cancer Lett. 2007 Jul 8;252(1):43-54. Epub 2007 Jan 16.
PMID: 17223259
doi:10.1016/j.canlet.2006.12.001
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