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Matti Narkia

Maté: a risk factor for oral and oropharyngeal cancer - Oral Oncol. 2002 Oct;... - 0 views

www.oraloncology.com/...abstract

2002 October study review epidemiological humans Mate Maté Ilex_paraguariensis yerba drink cancer risk oral head_and_neck head_and_neck_cancer hnca scchn oropharyngeal nutrition medline cancer_risk risk_factor

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  • Matti Narkia on 23 Apr 09
     
    Maté: a risk factor for oral and oropharyngeal cancer. Goldenberg D. Oral Oncol. 2002 Oct;38(7):646-9. Review. PMID: 12167417
Matti Narkia

Multiple roles for CD4+ T cells in anti-tumor immune responses. - Wiley InterScience ::... - 0 views

www3.interscience.wiley.com/...abstract

2008 April study review CD4 T-helper immunotherapy cancer vaccines cancer_vaccines anti-cancer anticancer immune respose immunity Th1 IFN-gamma TGF-beta Tregs T-regs T-regulator Th CTL cytotoxic_T-lymphocytes cytotoxic T-lymphocytes

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  • Matti Narkia on 16 Apr 09
     
    Multiple roles for CD4+ T cells in anti-tumor immune responses. Kennedy R, Celis E. Immunol Rev. 2008 Apr;222:129-44. Review. PMID: 18363998 DOI: 10.1111/j.1600-065X.2008.00616.x
Matti Narkia

Interleukin 2-mediated conversion of ovarian cancer-associated CD4+ regulatory T cells ... - 0 views

journals.lww.com/...articleviewer.aspx

2009 February study research in_vitro ex_vivo ovarian cancer ovarian_cancer IL-2-mediated conversion IL-2 CD4 Tregs T-regs T-regulator IL-17 T-Helper TH TR anticancer anti-cancer immunity immune function TH17

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  • Matti Narkia on 16 Apr 09
     
    Interleukin 2-mediated conversion of ovarian cancer-associated CD4+ regulatory T cells into proinflammatory interleukin 17-producing helper T cells. Leveque L, Deknuydt F, Bioley G, Old LJ, Matsuzaki J, Odunsi K, Ayyoub M, Valmori D. J Immunother. 2009 Feb-Mar;32(2):101-8. PMID: 19238008 doi: 10.1097/CJI.0b013e318195b59e Thus, although the impact of TH17 cells on the evolution of EOC remains to be established, our data suggest that local IL-2 treatment in ovarian cancer may result in the conversion of tumor-associated Treg into TH17 cells, relieve Treg-mediated suppression, and contribute to enhance antitumor immunity.
Matti Narkia

Inhibition of suppressor T lymphocytes (Ts) by cimetidine. - J Immunol. 1987 May - 0 views

www.jimmunol.org/...2760

1987 May study research in_vivo animal_stydy contrasuppression cyclophosphamide cimetidine T-suppressor Tregs T-regs Ts inhibition inhibitors immunotherapy medline immune function immunity immunostimulants

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  • Matti Narkia on 14 Apr 09
     
    Inhibition of suppressor T lymphocytes (Ts) by cimetidine. Sahasrabudhe DM, McCune CS, O'Donnell RW, Henshaw EC. J Immunol. 1987 May 1;138(9):2760-3. PMID: 2952721 Cyclophosphamide (CY) is the most extensively studied inhibitor of suppressor T lymphocyte (Ts) function. However, repeated administration of CY can abrogate sensitization. Therefore, we were interested in identifying noncytotoxic inhibitors of Ts function as adjuncts in the immunotherapy of Ts-inducing murine tumors. The effect of cimetidine (a histamine type 2 receptor antagonist) and diphenhydramine (a histamine type 1 receptor antagonist) on the Ts mediating tolerance to 2,4-dinitrofluorobenzene was studied. We report our data regarding the specific inhibition of Ts by cimetidine.
Matti Narkia

Multi-targeted therapy of cancer by omega-3 fatty acids - Cancer Lett. 2008 Oct 8 - 0 views

www.cancerletters.info/...abstract

2008 October study review humans multi-targeted therapy treatment cancer omega-3 omega-6 dietary fat dietary_fat diet PUFA fish_oil fish prevention cancer_prevention nutrition medline PUFAs

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  • Matti Narkia on 14 Apr 09
     
    Multi-targeted therapy of cancer by omega-3 fatty acids. Berquin IM, Edwards IJ, Chen YQ. Cancer Lett. 2008 Oct 8;269(2):363-77. Epub 2008 May 13. Review. PMID: 18479809 doi:10.1016/j.canlet.2008.03.044
Matti Narkia

Nutrient Intake and Immune Function of Elderly Subjects - J Am Diet Assoc. 2008 Dec - 0 views

www.adajournal.org/...abstract

2008 December study research epidemiological cross-sectional humans elderly older old immune function immune_function immunity selenium sodium DHA EPA omega-3 vitamin_A vitamin A nutrition medline nutrient intake nutrients

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  • Matti Narkia on 13 Apr 09
     
    Nutrient intake and immune function of elderly subjects. Wardwell L, Chapman-Novakofski K, Herrel S, Woods J. J Am Diet Assoc. 2008 Dec;108(12):2005-12. PMID: 19027403 doi:10.1016/j.jada.2008.09.003
Matti Narkia

Is regular exercise a friend or foe of the aging immune system? A systematic review. - ... - 0 views

journals.lww.com/...articleviewer.aspx

2008 November study review systematic humans elderly older old regular exercise physical_activity friend foe aging immune system immune_system immunity medline health

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  • Matti Narkia on 13 Apr 09
     
    Is regular exercise a friend or foe of the aging immune system? A systematic review. Haaland DA, Sabljic TF, Baribeau DA, Mukovozov IM, Hart LE. Clin J Sport Med. 2008 Nov;18(6):539-48. Review. PMID: 19001887 doi: 10.1097/JSM.0b013e3181865eec
Matti Narkia

High Prevalence of Vitamin D Deficiency Despite Supplementation in Premenopausal Women ... - 0 views

jco.ascopubs.org/...2151

2009 May study research clinical_trial humans premenopausal women patients breast cancer breast_cancer vitamin_D deficiency high prevalence despite supplementation undergoing adjuvant chemotherapy 25ohd nutrition

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  • Matti Narkia on 26 Aug 09
     
    High prevalence of vitamin D deficiency despite supplementation in premenopausal women with breast cancer undergoing adjuvant chemotherapy. Crew KD, Shane E, Cremers S, McMahon DJ, Irani D, Hershman DL. J Clin Oncol. 2009 May 1;27(13):2151-6. Epub 2009 Apr 6. PMID: 19349547 DOI: 10.1200/JCO.2008.19.6162 Conclusion Vitamin D deficiency is highly prevalent in women with breast cancer. The current recommended dietary allowance of vitamin D is too low to increase serum 25-OHD greater than 30 ng/mL. Optimal dosing for bone health and, possibly, improved survival has yet to be determined.
Matti Narkia

Vitamin D and Cancer Mini-Symposium: The Risk of Additional Vitamin D - 0 views

www.annalsofepidemiology.org/...abstract

2009 July study review humans Vieth vitamin_D cancer dosage dosing UL risk assessment safety toxicity 25ohd calcidiol calcitriol nutrition medline hypercalcemia clinical_trials evidence supplementation

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  • Matti Narkia on 26 Aug 09
     
    Evidence from clinical trials shows, with a wide margin of confidence, that a prolonged intake of 10,000IU/d of vitamin D3 poses no risk of adverse effects for adults, even if this is added to a rather high physiologic background level of vitamin D. Vitamin D and cancer mini-symposium: the risk of additional vitamin D. Vieth R.\nAnn Epidemiol. 2009 Jul;19(7):441-5. Epub 2009 Apr 11. PMID: 19364661 doi:10.1016/j.annepidem.2009.01.009
Matti Narkia

A 22-y prospective study of fish intake in relation to prostate cancer incidence and mo... - 0 views

www.ajcn.org/...1297

2008 November ajcn study research epidemiological fish intake prostate cancer incidence prostate_cancer PCa survival death risk mortality cancer_mortality seafood omega-3 PCa_mortality nutrition medline Stampfer

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  • Matti Narkia on 29 Mar 09
     
    A 22-y prospective study of fish intake in relation to prostate cancer incidence and mortality. Chavarro JE, Stampfer MJ, Hall MN, Sesso HD, Ma J. Am J Clin Nutr. 2008 Nov;88(5):1297-303. PMID: 18996866 Conclusion: These results suggest that fish intake is unrelated to prostate cancer incidence but may improve prostate cancer survival.
Matti Narkia

Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostat... - 0 views

clincancerres.aacrjournals.org/...1078-0432.CCR-08-2503v1

2009 March study research epidemiological case-control humans men prostate cancer prostate_cancer advanced agressive risk cancer_risk omega-3 PUFA risk_reduction long-chain EPA DHA COX-2 gene genetics nutrition medline inflammation PCa

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  • Matti Narkia on 28 Mar 09
     
    Dietary Omega-3 Fatty Acids, Cyclooxygenase-2 Genetic Variation, and Aggressive Prostate Cancer Risk. Fradet V, Cheng I, Casey G, Witte JS. Clin Cancer Res. 2009 Mar 24. [Epub ahead of print] PMID: 19318492 DOI: 10.1158/1078-0432.CCR-08-2503
Matti Narkia

The influence of processing and preservation on the retention of health-promoting compo... - 0 views

www3.interscience.wiley.com/...abstract

2007 March study research in_vitro broccoli chilling freezing cooking heating boiling steaming microwaving sulforaphane vitamin_C retention nutrition medline

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  • Matti Narkia on 27 Mar 09
     
    The influence of processing and preservation on the retention of health-promoting compounds in broccoli. Galgano F, Favati F, Caruso M, Pietrafesa A, Natella S. J Food Sci. 2007 Mar;72(2):S130-5. PMID: 17995854 DOI: 10.1111/j.1750-3841.2006.00258.x
Matti Narkia

Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up ... - 0 views

jnci.oxfordjournals.org/...djp037v1

2009 March JNCI study research clinical_trial rct humans vitamin vitamins supplements supplementation selenium vitamin_E beta-carotene gastric cancer gastric_cancer all-cause all-causes mortality nutrition all-cause_mortality cancer_mortality China

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  • Matti Narkia on 25 Mar 09
     
    You-Lin Qiao, Sanford M. Dawsey, Farin Kamangar, Jin-Hu Fan, Christian C. Abnet, Xiu-Di Sun, Laura Lee Johnson, Mitchell H. Gail, Zhi-Wei Dong, Binbing Yu, Steven D. Mark, and Philip R. Taylor. Total and Cancer Mortality After Supplementation With Vitamins and Minerals: Follow-up of the Linxian General Population Nutrition Intervention Trial. Journal of the National Cancer Institute, 2009 March 24; DOI: 10.1093/jnci/djp037
Matti Narkia

In vitro and in vivo anti-tumor effects of Astragalus membranaceus - Cancer Lett. 2007 ... - 0 views

www.cancerletters.info/...abstract

2007 July study research in_vitro in_vivo animal_study Astragalus_membranaceus Astragalus herb herbs herbal_medicine Huangqi anti-cancer anticancer cancer TNF lymphokine-activated killer cells immune mechanism restoration immunity response medline

shared by Matti Narkia on 11 Apr 09 - Cached
  • Matti Narkia on 11 Apr 09
     
    In vitro and in vivo anti-tumor effects of Astragalus membranaceus. Cho WC, Leung KN. Cancer Lett. 2007 Jul 8;252(1):43-54. Epub 2007 Jan 16. PMID: 17223259 doi:10.1016/j.canlet.2006.12.001
Matti Narkia

Selenium and the immune response: 2. Enhancement of murine cytotoxic T-lymphocyte and n... - 0 views

www.jleukbio.org/...215

1989 stydy research in_vivo animal_study mice selenium cell-mediated immune response CIMR immunity innate T-lymphocytes natural_killer_cells NK_cells cytotoxicity medline nutrition cancer incidence cytotoxic

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  • Matti Narkia on 10 Apr 09
     
    2: Selenium and the immune response: 2. Enhancement of murine cytotoxic T-lymphocyte and natural killer cell cytotoxicity in vivo. Petrie HT, Klassen LW, Klassen PS, O'Dell JR, Kay HD. J Leukoc Biol. 1989 Mar;45(3):215-20. PMID: 2564412
Matti Narkia

Vitamin D and Intervention Trials in Prostate Cancer: From Theory to Therapy - 0 views

www.annalsofepidemiology.org/...abstract

2009 February study review clinial_trials humans prostate cancer prostate_cancer PCa vitamin D vitamin_D calcitriol 1.25(OH)2D VDR paricalcitol analogues analogs medicine medline hypercalcemia prevention treatment therapy cholecalciferol mechanism

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  • Matti Narkia on 09 Apr 09
     
    Vitamin D and intervention trials in prostate cancer: from theory to therapy. Schwartz GG. Ann Epidemiol. 2009 Feb;19(2):96-102. Epub 2008 Jul 10. PMID: 18619854 doi:10.1016/j.annepidem.2008.03.007 This suggests that whereas vitamin D (e.g., cholecalciferol) might prevent prostate cancer, existing prostate tumors likely would require treatment with 1,25(OH)(2)D and/or its analogs. The major obstacle to the use of 1,25(OH)(2)D in patients therapeutically is the risk of hypercalcemia. Several maneuvers to reduce this risk, including pulse dosing and the use of less calcemic 1,25(OH)(2)D analogs, have been explored in Phase I-III clinical trials. Once merely a promise, vitamin D-based therapies for prostate cancer may soon be medical practice.
Matti Narkia

CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependen... - 0 views

www.nature.com/...6604904a.html

2009 March study review castration-refractory prostate cancer prostate_cancer PCa CRPC abiraterone CYP17 inhibitor inhibition androgen synthesis androgen_synthesis medicine medline abiraterone_acetate

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  • Matti Narkia on 09 Apr 09
     
    CYP17 blockade by abiraterone: further evidence for frequent continued hormone-dependence in castration-resistant prostate cancer. Ang JE, Olmos D, de Bono JS. Br J Cancer. 2009 Mar 10;100(5):671-5. Epub 2009 Feb 17. PMID: 19223900 doi:10.1038/sj.bjc.6604904
Matti Narkia

Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms... - 0 views

jco.ascopubs.org/...4563

2008 Ocober study research clinical_trial phase_I phase_I_trial humans men prostate cancer prostate_cancer PCa aggressive advanced castration-resistant CRPC abiraterone_acetate abiraterone CYP17 inhibitor medicine medline PSA anticacner anti-cancer

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  • Matti Narkia on 09 Apr 09
     
    Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven. Attard G, Reid AH, Yap TA, Raynaud F, Dowsett M, Settatree S, Barrett M, Parker C, Martins V, Folkerd E, Clark J, Cooper CS, Kaye SB, Dearnaley D, Lee G, de Bono JS. J Clin Oncol. 2008 Oct 1;26(28):4563-71. Epub 2008 Jul 21. PMID: 18645193 DOI: 10.1200/JCO.2007.15.9749
Matti Narkia

Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth... - 0 views

journals.lww.com/...articleviewer.aspx

2008 May study research in_vitro in_vivo pancreatic cancer growth pancreatic_cancer omega-3 omega-6 ratio omega-6_omega-3 PUFA PUFAs COX-2 PGE2 PGE3 nutrition medline dietary intake PaCa

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  • Matti Narkia on 05 Apr 09
     
    Opposing effects of n-6 and n-3 polyunsaturated fatty acids on pancreatic cancer growth. Funahashi H, Satake M, Hasan S, Sawai H, Newman RA, Reber HA, Hines OJ, Eibl G. Pancreas. 2008 May;36(4):353-62. PMID: 18437081 doi: 10.1097/MPA.0b013e31815ccc44
Matti Narkia

Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell... - 0 views

www.journals.elsevierhealth.com/...abstract

2003 June study research clinical_trial rct humans patients advanced non-small cell lung cancer non-small_cell lung_cancer NSLC palliative treatment Coriolus_versicolor polysaccharide peptide Coriolus mushroom mushrooms herb herbs herbal_medicine PSK PSP

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  • Matti Narkia on 11 Apr 09
     
    Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer. Tsang KW, Lam CL, Yan C, Mak JC, Ooi GC, Ho JC, Lam B, Man R, Sham JS, Lam WK. Respir Med. 2003 Jun;97(6):618-24. PMID: 12814145 doi:10.1053/rmed.2003.1490
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