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Katie Rigdon

Cosmetic Chemistry Lab Uses New Pentapharm Peptide In Potent Anti-Aging Eye Serum - 0 views

    • Katie Rigdon
       
      Anticoagulants, antifibrinolytics and haemostatics are three more topics to pursue under teh larger topic of anti-aging cosmetics
  • anticoagulants, antifibrinolytics and haemostatics.
  • Syn-Coll,
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  • Syn-Coll stimulates the collagen synthesis in human fibroblasts. Skin aging and chronic UV exposure particularly, leads to degenerative changes in skin. The degenerative changes in skin are characterized by distinct alterations in the composition of the dermal extra cellular matrix.
  • Tissue growth factor is known as the key element in the synthesis of collagen and binds to a particular sequence in the TSP molecule. This sequence is known as ARG-PHE-LYS.
  • As a molecule able to activate TGF, Syn-Coll is considered to be an ideal aqueous based peptide. It contains a unique sequence designed to mimic the human body's own mechanism to product collagen via TGF. Accordingly, Syn-Coll actively compensates for any collagen deficit, thus making the skin look younger and rejuvenated.
  • The results of the Syn-Coll clinical studies are astounding. After 84 days of twice-daily application, a panel of 60 volunteers experienced 2.5% Syn-Coll parameters average relief (Rz) and maximum relief (Rt) significantly decreased by -12%: -22 μm and -36 μm respectively (p= 0.05) characterizing smoothing and anti wrinkle effects.
    • Katie Rigdon
       
      Looks like this ingredient actually works!
Amanda Jara

Deodorant paraben chemicals 'found in breast tumours' - Health News - NHS Choices - 2 views

  • The researchers detected one or more parabens in 99% of tissue samples (158 of 160 analysed) and all five parabens in 60% of samples (96 of 160)
    • Andrew Kang
       
      Unbelievable - 99% is a ridiculously high statistic. You're right - it would be interesting to talk about parabens and their usefulness in cosmetics, as so many products use them. And perhaps attention is now being brought to their negative effects as well.
    • Jenny Mu
       
      But just because parabens are detected in breast cancer samples, does that necessarily mean that they are the cause?
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    This article talks about breast cancer and parabens, but I think that information about parabens alone could be a very good topic to discuss.  Parabens are found in many shampoos, moisturizers, deodorants, gels, etc. 
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    We should definitely look more into parabens, because they are found everywhere. But I think it's really interesting how this commonplace chemical in everyone's chapsticks and shampoos and everything is actually found in 99% of breast cancer tissue. I think the concept that these chemicals may cause breast cancer seems a bit spurious, but maybe after reading more articles about parabens, we can find out more about the chemical.
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    wow this is a really interesting article! I think Jenny is right though- it doesn't look like it can be concluded that these parabens cause breast cancer. The article said that parabens were also found in 100% of the urine samples taken from children and pregnant women so it looks like they are also found in normal healthy people! Are you thinking of writing your blog post on this Amanda?
Jenny Mu

Beauty Antioxidants: Facial Attraction | Nutritional Outlook - 0 views

  • And while these are all products that are topically applied—a concept consumers are familiar and comfortable with—more consumers are coming around to the idea that the same ingredients that are found in lotions and potions might also be able to influence outward appearance when incorporated in the diet.
    • Jenny Mu
       
      Which way is better? topical treatments or oral ingestion
  • “There is human clinical evidence that these yellow carotenoids act like internal sunscreen to protect and improve skin health,” he says, referring to a 2007 study that tested the oral and topical effects of lutein and zeaxanthin over 12 weeks. (P Palombo et al., “Beneficial long-term effects of combined oral/topical antioxidant treatment with the carotenoids lutein and zeaxanthin on human skin: a double-blind, placebo-controlled study,” Skin Pharmacology and Physiology, vol. 20, no. 4 (2007):199-210.) “Statistically significant, favorable effects were seen on three skin function outcomes, including hydration, photoprotection, and lipid damage,” says Bhattacharya. “Higher oral doses of zeaxanthin were shown to provide effective protection against sunburn, which could help reduce the risks of skin cancer, premature aging, and wrinkling.”
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    • Jenny Mu
       
      What inside them is acting like an internal sunscreen? Chemically, how does it work?
  • Pycnogenol is one of the few antioxidants shown to effectively neutralize all oxygen radical species. It says this is especially important to the skin, as even low-to-moderate UV exposure generates oxygen radicals in the dermis.
    • Jenny Mu
       
      Neutralization of oxygen radical species. Once again, we should look into the chemical process of how this happens. The transfer of electrons etc.
Andrew Kang

'Green chemistry' sees bright future in detergents, makeup - The China Post - 1 views

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    interesting to look at the chemistry of green science especially in the field of cosmetics
  •  
    Andrew - what do you find interesting about this article?
Andrew Kang

'Nano' labelling will reveal little about products - Health News - News - WalesOnline - 2 views

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    Another article - this time more recent. This shows just how much nano-chemistry is prevalent in today's world of cosmetics that they are now making it mandatory in the EU to label products as "nano" to inform the consumer about the possible health risk. 
Andrew Kang

Safety of Nano-Cosmetics Questioned : NPR - 0 views

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    This article is from 2006. Although a bit dated, it is still worth reading. It poses the possibility of health risks of nano-cosmetics which we know gold colloids utilize. 
Amanda Jara

Skin Deep - Gold Face Cream - A Costly Leap of Faith - NYTimes.com - 2 views

    • Amanda Jara
       
      we can look up other common ingredients that cause allergic reactions...ie arbutin
    • Katie Rigdon
       
      I think allergies could be a really interesting topic to add to our blog because, like Jenny said, we are kind of all over the place and I think we need some topics so skin allergies (to things in cosmetics) could be one of them!
    • Jenny Mu
       
      But we also have to keep the topic focused on chemistry, and allergies could really easily go into biology or something like that. but there is a chemistry side to allergies too, so maybe that could work
    • Andrew Kang
       
      The article kept stressing the benefits of colloidal gold as opposed to gold in flakes or just applied to the skin. Perhaps we could look at nanochemistry in cosmetics - it was nanoparticles that gave the colloidal cream its advantage and with anything you apply to your skin perhaps there is consideration given to the substance on the molecular scale for its efficacy.
    • Jenny Mu
       
      But we should also consider the element itself. Whether in nanoparticles or in flakes, what scientific evidence is there that gold is good for the skin? Or is it just one big, expensive scam...
Katie Rigdon

Allergies and Cosmetics - 2 views

  •  
    Interesting article about causes of skin allergies from WebMD. Looks like fragrances can play a big part in allergies and it also looks like there are some things that you can do to prevent these allergic reactions.
  •  
    Interesting - but we have to be careful not to stray into the biology of allergies when explaining why they occur.
Amanda Jara

Skin Deep - Gold Face Cream - A Costly Leap of Faith - NYTimes.com - 0 views

    • Amanda Jara
       
      Contradicting what the dermatologist said about gold not having any affect on skin. Ballard, a marketing executive talks about all the benefits.  Is there any scientific data or research to back her claims?
Jenny Mu

Chemistry | CosmeticsAndToiletries.com - 1 views

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    The more chemistry-ish side to cosmetics. Very helpful..
Jenny Mu

Cosmetic Chemistry - Chemistry Encyclopedia - structure, water, examples, metal, number... - 3 views

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    This site explains all the basics of the chemistry behind cosmetics, such as lotions, moisturizers, chapsticks, etc.
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    we should pick something that interests us from this site, and go from there, because our topic is really broad, and I feel like right now, we are all over the place.
Amanda Jara

http://ntp.niehs.nih.gov/files/Arbutin.pdf - 1 views

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    Looking even from the abstract, we can get some info on abutin - the chemical in the gold mask that cause irritation
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    I think the allergic reaction to the arbutin was only specific for that one person who wrote the article. From this review article, it seems as though arbutin is used in a variety of skin lightening products, because it reduces the melanin production, which causes dark spots and what not.
Jenny Mu

Skin Deep - Gold Face Cream - A Costly Leap of Faith - NYTimes.com - 1 views

  • People who sell creams with visible gold flecks talk about the ability of those flecks to warm the skin and make it conducive to other ingredients. People who sell gold in nano form — that is, in microscopic particles suspended in a liquid mixture known as a colloid — look down on this crowd, saying that gold can confer benefits only when it is broken down small enough to penetrate the skin.
  • But is it true that gold has therapeutic qualities? That depends if you ask someone who is selling it suspended in cream or someone who went to medical school. Dermatologists speak with one voice, saying that gold cannot help you, but it absolutely can hurt you, causing inflammatory reactions like contact dermatitis (which may be what happened to me). In high doses, gold can be toxic, but these products probably don’t contain enough of it to make that happen, doctors say.
  • At best, they do nothing, and at worst, they can give you irritation of the skin,”
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  • “intensive medical searches on this very ingredient” and found that “there are absolutely no scientific studies that show that gold has any effect in firming or revitalizing the skin, nor that it reduces wrinkles or gives skin a plumped, golden glow.”
  • “Colloidal gold does help to maintain your skin’s elasticity and firmness,” she said. “Gold itself is known to have very soothing benefits to it.”
  • a line of products that contain colloidal platinum — including a cream that costs $1,000 an ounce
  • outlined a number of benefits: gold, she said, is hypoallergenic, stimulates blood circulation, reduces sunspots and acts as an antioxidant.
  • “The gold actually acts like a small charger, because it’s metal and we have electricity in our bodies,” she said. “Whenever gold comes into contact with our bodies, it gives a boost of activity, which is good for restoring the lost elasticity properties of the tissue.”
  • Cosmetics makers also habitually cite the use of gold in medicine, where it is given to patients with rheumatoid arthritis and has been used — only experimentally — as a possible cancer treatment. Debabrata Mukhopadhyay, a professor and cancer researcher at the Mayo Clinic, said that while gold nanoparticles show promise, they are “highly toxic when injected in high doses in mice.” And the size of the nanoparticles matters a lot, he said, adding that it was unclear if the particles in the gold face creams were the right size to penetrate the skin.
  • “As a scientist, I am very skeptical unless I see research,”
  • Ms. Genovese pointed out that people keep buying her company’s gold line because they perceive that it works.
    • Jenny Mu
       
      Gold nanoparticles do have a lot of applications in research, but in skincare??
    • Jenny Mu
       
      Clearly, there are no benefits in gold face creams.
    • Jenny Mu
       
      This just goes to show that these cosmetic companies are just using whatever material is more expensive in their face creams so they can jack up the price. First gold, then platinum...
    • Jenny Mu
       
      This seems like a load of nonsense, but maybe this warrants further research.....
    • Jenny Mu
       
      placebo effect?
Jenny Mu

Shiseido introduces the most expensive skin cream for anniversary - Long Island Spa Tre... - 1 views

  • The NPD group apparently reported that 86% of women asked admit to using makeup with skincare benefits with the thought that consumers are getting more “bang for their buck.”
    • Jenny Mu
       
       I was just wondering, what justifies the extreme prices of these skincare products. What materials or chemical processes are needed to produce them, and do they really have any effect? Personally, if I was paying $13,300, I would expect it to do a lot more than just moisturize or reduce fine lines.
  • For around $13,300,
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