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Individuals who need organ transplant surgery typically include those with: End-Stage Organ Failure: Severe and irreversible failure of vital organs such as the heart, liver, kidneys, lungs, or pancreas. Chronic Diseases: Long-term conditions like cirrhosis, cardiomyopathy, chronic kidney disease, or chronic obstructive pulmonary disease (COPD). Genetic Disorders: Conditions like cystic fibrosis or polycystic kidney disease. Acute Organ Damage: Sudden organ failure due to trauma, infection, or poisoning. Congenital Defects: Birth defects that impair organ function.