Deregulated EGFR Signaling during Lung Cancer Progression: Mutations, Amplicons, and Au... - 0 views
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Matthew Links on 22 Sep 08fantastic review the concept of autocrine loops is key
EGFR and KRAS mutations as criteria for treatment with tyrosine kinase inhibitors: retr... - 0 views
Differential Effects of Gefitinib and Cetuximab on Non-small-cell Lung Cancers Bearing ... - 0 views
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of interest becusae compare gefitinib and cetuximab . need careful attention to methods for cetux but leaves question of synergy open.
SpringerLink - Journal Article - 0 views
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interesting paper both becuase it includes cell cycle effects of ras transfection but also becuase of the data on src as an alternate mechanism
Stimulated PI3K-AKT Signaling Mediated through Ligand or Radiation-Induced EGFR Depends... - 0 views
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key paper for pi3kinase hypothesis for deleteriou effect of kras egfr inhibition
NEJM -- Oncogenes and Cancer - 0 views
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this is a short course of essential cancer biology
Coordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epide... - 0 views
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anotherlandmark paper
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of hea... - 0 views
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landmark paper for eGFR resistance and key concept
Inhibition of NF-{kappa}B sensitizes non-small cell lung cancer cells to chemotherapy-i... - 0 views
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this paper highlights the role of NF-kappa in cell survival after gem it fits into the signalling survival versus arrest concept
h_vegfPathway - 0 views
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good pathway
h_rhoPathway - 0 views
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this pathway site is very usefull. this pathway useful for stephen
About RNA interference (RNAi) on CGAP - 0 views
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excellent starting point for siRNA work
TCS_Angio96.pdf (application/pdf Object) - 0 views
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useful kit not sure about using methodology ourselves
fixed dose rate gem - 0 views
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uses very low dose gem over 6 hrs
fixed dose rate gem - 0 views
The Combination of Epidermal Growth Factor Receptor Inhibitors with Gemcitabine and Rad... - 0 views
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