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Deregulated EGFR Signaling during Lung Cancer Progression: Mutations, Amplicons, and Au... - 0 views

cancerpreventionresearch.aacrjournals.org/...156 egfr
shared by Matthew Links on 22 Sep 08 - Cached
  • Matthew Links on 22 Sep 08
     
    fantastic review the concept of autocrine loops is key
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Differential Effects of Gefitinib and Cetuximab on Non-small-cell Lung Cancers Bearing ... - 0 views

jnci.oxfordjournals.org/...1185 egfr
shared by Matthew Links on 22 Sep 08 - Cached
  • Matthew Links on 22 Sep 08
     
    of interest becusae compare gefitinib and cetuximab . need careful attention to methods for cetux but leaves question of synergy open.
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SpringerLink - Journal Article - 0 views

www.springerlink.com/...qu17jkr626218402 egfr
shared by Matthew Links on 22 Sep 08 - Cached
  • Matthew Links on 22 Sep 08
     
    interesting paper both becuase it includes cell cycle effects of ras transfection but also becuase of the data on src as an alternate mechanism
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Stimulated PI3K-AKT Signaling Mediated through Ligand or Radiation-Induced EGFR Depends... - 0 views

mcr.aacrjournals.org/...863 egfr
shared by Matthew Links on 22 Sep 08 - Cached
  • Matthew Links on 22 Sep 08
     
    key paper for pi3kinase hypothesis for deleteriou effect of kras egfr inhibition
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NEJM -- Oncogenes and Cancer - 0 views

content.nejm.org/...502 biology
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    this is a short course of essential cancer biology
1More

Coordinated Epidermal Growth Factor Receptor Pathway Gene Overexpression Predicts Epide... - 0 views

cancerres.aacrjournals.org/...2841 egfr
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    anotherlandmark paper
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Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of hea... - 0 views

mct.aacrjournals.org/...1683 egfr
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    landmark paper for eGFR resistance and key concept
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Inhibition of NF-{kappa}B sensitizes non-small cell lung cancer cells to chemotherapy-i... - 0 views

ats.ctsnetjournals.org/...930 gemcitabine
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    this paper highlights the role of NF-kappa in cell survival after gem it fits into the signalling survival versus arrest concept
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h_vegfPathway - 0 views

cgap.nci.nih.gov/...h_vegfPathway angiogenesis
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    good pathway
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h_rhoPathway - 0 views

cgap.nci.nih.gov/...h_rhoPathway angiogenesis
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    this pathway site is very usefull. this pathway useful for stephen
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About RNA interference (RNAi) on CGAP - 0 views

cgap.nci.nih.gov/RNAi pharmacology sirna
shared by Matthew Links on 12 Sep 08 - Cached
  • Matthew Links on 12 Sep 08
     
    excellent starting point for siRNA work
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TCS_Angio96.pdf (application/pdf Object) - 0 views

www.tcscellworks.co.uk/...TCS_Angio96.pdf angiogenesis
shared by Matthew Links on 04 Sep 08 - No Cached
  • Matthew Links on 04 Sep 08
     
    useful kit not sure about using methodology ourselves
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fixed dose rate gem - 0 views

www.sciencedirect.com/...6199857ab3933bb95cc896c4a991b6 gemcitabine
shared by Matthew Links on 04 Sep 08 - Cached
  • Matthew Links on 04 Sep 08
     
    uses very low dose gem over 6 hrs
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