Best content in Seasons Wellness | Diigo - Groups

Increased Vascular Inflammation in Early Menopausal Women Is Associated with Hot Flush Severity

Fri, 25 May 2012 14:09:10 -0000

Comments:

increased inflammatory markers associated with increased hot flash severity in menopausal women. This is also associated with increased cardiovascular disease. Interesting that progesterone has anti-inflammatory properties. So, therapy to reduce hot flashes should include inflammation reduction. - Nathan Goodyear

Tags: inflammation, cytokines, hot flashes, menopause, women, cardiovascular disease, severity

by: Nathan Goodyear

Insulin Up-Regulates Natriuretic Peptide Clearance Receptor Expression in the Subcutaneous Fat Depot in Obese Subjects: A Missing Link between CVD Risk and Obesity?

Fri, 25 May 2012 13:58:32 -0000

Comments:

elevated insulin in insulin resistance decreases circulating Natriuretic peptide. This provides a direct link between obesity and cardiovascular disease - Nathan Goodyear

Tags: insulin, insulin resistance, obesity, overweight, NP, natriuretic peptide, cardiovascular disease

by: Nathan Goodyear

Progesterone Receptor-A and -B Have Opposite Effects on Proinflammatory Gene Expression in Human Myometrial Cells: Implications for Progesterone Actions in Human Pregnancy and Parturition

Fri, 25 May 2012 12:39:37 -0000

Comments:

Progesterone is known to have anti-inflammatory action. This study looked at the anti-inflammatory action of progesterone on the myometrium of the uterus during pregnancy. The anti-inflammatory effect, in this study, was through Progesterone Receptor B. There was a change in the dominance to PR A late in pregnancy. This would promote inflammatory signaling and thus contractions with the onset of labor. - Nathan Goodyear

Tags: progesterone, progesterone receptors, PR A, PR, B pregnancy anti-inflammatory labor

by: Nathan Goodyear

Serum Leptin, Parathyroid Hormone, 1,25-Dihydroxyvitamin D, Fibroblast Growth Factor 23, Bone Alkaline Phosphatase, and Sclerostin Relationships in Obesity

Fri, 25 May 2012 12:28:42 -0000

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high leptin, high PTH, fibroblastic growth factor, and bone alkaline phosphatase associated with obesity. - Nathan Goodyear

Tags: leptin, PTH, obesity

by: Nathan Goodyear

826 papers on Vitamin D

Wed, 23 May 2012 12:26:45 -0000

Comments:

826 research articles on Vitamin D - Nathan Goodyear

Tags: vitamin D, D, vitamin

by: Nathan Goodyear

Vitamin D and autism: Clinical review. [Res Dev Disabil. 2012] - PubMed - NCBI

Tue, 22 May 2012 13:10:38 -0000

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Vitamin D deficiency may play a role in autism. Though this may seem logical, through NF-KappaB inhibition, the mode of protection may be more in pregnancy. I believe that the in-utero environment is setting up our children for increased ASD rates. Then add in the manner in which we treat our children as infants with massive vaccinations. - Nathan Goodyear

Tags: Vitamin D, autism, ASD

by: Nathan Goodyear

Apigenin Induces Apoptosis and Blocks Growth of Medroxyprogesterone Acetate-Dependent BT-474 Xenograft Tumors

Tue, 22 May 2012 12:43:12 -0000

Comments:

Finally, something that lowers the risk associated with synthetic progestins. Progestins are progesterone pretenders that increase breast cancer. Apigenin, a component of bioflavonoid, was shown to inhibit growth and intact cause cell death. - Nathan Goodyear

Tags: apigenin, breast, cancer, flavonoid, bioflavonoid, medroxyprogesterone acetate, synthetic progestins, progestins

by: Nathan Goodyear

Reduced-Calorie Dietary Weight Loss, Exercise, and Sex Hormones in Postmenopausal Women: Randomized Controlled Trial

Tue, 22 May 2012 12:35:34 -0000

Comments:

Not surprising, but nice to see in study. Dr. McTiernan showed that weight loss as little as 5% reduces breast cancer risk. The reason? Decreased Testosterone production in women due to insulin resistance and decreased fat for aromatase conversion of Testosterone to Estradiol and decreased androstenedione to estrone. This study confirms the importance of the obesity epidemic to health. - Nathan Goodyear

Tags: obesity, obese, overweight, weight-loss, aromatase, breast, cancer, testosterone, estradiol, estrogen, hormones, women

by: Nathan Goodyear

Effect of exposure to p,p'-DDE on male hormone profile in Mexican flower growers -- Blanco-Muñoz et al. 69 (1): 5 -- Occupational and Environmental Medicine

Mon, 21 May 2012 15:59:06 -0000

Comments:

DDE in hispanic farm workers found to be inversely associated with testosterone. Again, DDE and other persistent organohalogen pollutants, work to lower testosterone in men. - Nathan Goodyear

Tags: DDE, persistent organohalogen pollutants, male, hormones, hormone, low, T, testosterone, men, mexican, environmental

by: Nathan Goodyear

Reproductive Hormone Levels in Men Exposed to Persistent Organohalogen Pollutants: A Study of Inuit and Three European Cohorts

Mon, 21 May 2012 15:55:51 -0000

Comments:

Review finds endocrine disruption from Organocholrides, also called persistent organohalogen pollutants. Common POP, would be DDE, DDT...

This is a review of several cohorts, but this follows the rest of the literature that these environmental toxicants are endocrine disruptors. - Nathan Goodyear

Tags: POP, organochlorides, endocrine disruptors, persistent organohalogen men pollutants, DDE, DDT, low, T, testosterone, hormone, male, hormones

by: Nathan Goodyear

JSTOR: Epidemiology, Vol. 13, No. 4 (Jul., 2002), pp. 454-458

Mon, 21 May 2012 15:49:22 -0000

Comments:

High DDE levels in African American men associated with a 23% lower Testosteone levels - Nathan Goodyear

Tags: DDE, environmental toxins, low, T, testosterone, men, endocrine disruptors

by: Nathan Goodyear

Testosterone substitution with a new transdermal, hydroalcoholic gel applied to scrotal or non-scrotal skin: a multicentre trial

Thu, 17 May 2012 12:56:37 -0000

Comments:

testosterone gel as effect, and better tolerated, than patch in androgen replacement in men. - Nathan Goodyear

Tags: testosterone, gel, andropause, men, androgens, androgen

by: Nathan Goodyear

US lowers cutoff for lead poisoning in young kids | Fox News

Wed, 16 May 2012 19:03:01 -0000

Comments:

new CDC guidelines lower lead toxicity levels in children. CDC: " there is no safe level of blood lead in children". If no level is safe in children, what about other age groups? - Nathan Goodyear

Tags: lead, toxicity, poisoning, children

by: Nathan Goodyear

OASIS

Wed, 16 May 2012 18:40:17 -0000

Comments:

I look forward to the published results of this study as this abstract references the WHI as the "same entry" criteria. I imagine the HRT would be the same too, but will wait to see. There is a serious problem with proper reporting of synthetic estrogens as bioidentical estrogens and synthetic progestins as bioidentical progesterone; Also, what is the dosage. Most individuals are massively overdosed. This study was said to be a "landmark". Could just be don't use synthetic hormones: which is what the WHI said. - Nathan Goodyear

Tags: breast, cancer, synthetic hormones, HRT, BHRT, bioidentical, hormones

by: Nathan Goodyear

Cruciferous Vegetable Consumption Linked to Improved Breast Cancer Survival Rates

Wed, 16 May 2012 17:42:38 -0000

Comments:

higher cruciferous vegetable intake associated with improved breast cancer survival rates according to Shanghai Breast Cancer Survival Study. - Nathan Goodyear

Tags: breast, cancer, cruciferous, vegetables, survival, treatment, shanghai breast cancer survival study

by: Nathan Goodyear

Excess Body Weight Associated With Increased Risk for Cancer Recurrence After Treatment for Prostate Cancer

Wed, 16 May 2012 17:37:44 -0000

Comments:

overweight and obesity associated with higher risk of prostate cancer recurrence. No surprise here. Excess fat will increase inflammatory cytokines and aromatase conversion of Testosterone to Estradiol: also producing inflammation. - Nathan Goodyear

Tags: prostate, cancer, obesity, overweight, men, recurrence, weight

by: Nathan Goodyear

JAMA Network | Archives of Internal Medicine | Combined Estrogen and Testosterone Use and Risk of Breast Cancer in Postmenopausal Women

Wed, 16 May 2012 17:11:57 -0000

Comments:

this study revealed increased breast cancer risk in women on "estrogen" and "testosterone" therapy. Now, several problems here: first, are these synthetic hormone or bioidentical. Second, the dosages appear, in what is written, to be supra physiologic. Third, giving supra physiologic estradiol and testosterone will obviously create imbalances and growth potential. Fourth, how were the women evaluated prior to starting hormone therapy and then were they remonitered (unlikely), fifth, were hormone metabolites evaluated (too, also unlikely). This study has serious flaws and very little can be extrapolated other than: don't take supra physiologic hormone levels without appropriate evaluation. Enough said - Nathan Goodyear

Tags: hormones, synthetic, bioidentical, BHRT, breast, cancer, estrogen, testosterone

by: Nathan Goodyear

Effects of a Caloric Restriction Weight Loss Diet and Exercise on Inflammatory Biomarkers in Overweight/Obese Postmenopausal Women: A Randomized Controlled Trial

Wed, 16 May 2012 16:54:16 -0000

Comments:

weight loss results in reduced IL-6, CRP, and other markers of inflammation. - Nathan Goodyear

Tags: weight-loss, inflammation, CRP, IL-6, overweight

by: Nathan Goodyear

ATSDR - Substances Map Results Page

Wed, 16 May 2012 12:36:29 -0000

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documented cadmium sites in Louisiana - Nathan Goodyear

Tags: cadmium, Louisiana, maps, heavy metals

by: Nathan Goodyear

Common environmental contaminant, cadmium, linked to rapid breast cancer cell growth

Wed, 16 May 2012 12:29:10 -0000

Comments:

cadmium increases growth potential of breast cancer. No surprise, cadmium is a classic endocrine disruptor that mimics estrogen. - Nathan Goodyear

Tags: cadmium, breast, cancer, endocrine disruptor, xenoestrogen, estrogen, environmental

by: Nathan Goodyear