HSV infections are rising worldwide. It is near epidemic in many pockets the united states and Europe. There is still not really a crediable vaccine coming. Summary: In comparison with CENTER HerpeSelect 1 and 2 IgG it can be shown that in set 1 and 2 the new MIKROGEN recomLine HSV-1 & HSV-2 IgG experienced in 34, 7% (17/49) of the samples a better sensitivity for the HSV lysate antigen. Furthermore in group 1 in 16, 3% (9/49) in the samples a higher reactivity for gG1 or gG2 was found.
Remark: The differentiation between some sort of primary or recurrent HSV infection is just possible if the determination of antibodies (type-specific antibodies for HSV-1 and HSV-2) and virus isolation is conducted simultaneously. Especially if a presumptive diagnosis for herpes genitalis in pregnancy exists the differentiation of primary or recurrent infection is actually of much importance. The best significance of the findings is given if patient samples (smear and blood) are taken before you start of the infection.
In comparison with CENTER HerpeSelect 1 and 2 IgG it can be shown that in set 1 and 2 the new MIKROGEN recomLine HSV-1 & HSV-2 IgG experienced in 34, 7% (17/49) of the samples a better sensitivity for the HSV lysate antigen. Furthermore in group 1 in 16, 3% (9/49) in the samples a higher reactivity for gG1 or gG2 was found.
Remark:
The differentiation between some sort of primary or recurrent HSV infection is just possible if the determination of antibodies (type-specific antibodies for HSV-1 and HSV-2) and virus isolation is conducted simultaneously. Especially if a presumptive diagnosis for herpes genitalis in pregnancy exists the differentiation of primary or recurrent infection is actually of much importance. The best significance of the findings is given if patient samples (smear and blood) are taken before you start of the infection.
Mikrogen recomLine HSV 1 & 2